Central vascular flow patterns in the alligator Alligator mississipiensis.
Central vascular flow patterns in the alligator Alligator mississipiensis.
复制标题
密西西比短吻鳄的中央血管血流模式。
DOI：
10.1152/ajpregu.1995.269.5.r1133
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Greene,ER
中科院分区：
文献类型：
--
作者：
Malvin,GM;Hicks,JW;Greene,ER
许多不同的流动模式已被描述通过鳄鱼爬行动物的中央循环。我们测试的假设，迷走神经刺激促进右向左（R-L）在鳄鱼分流。使用三种方法，在刺激完整的左迷走神经之前和期间，研究了流动模式。1)用气体探头同时连续测量心房和主动脉PO 2。2)用血液示踪剂（氦）跟踪心房流出。3)用超声心动图评估血流。迷走神经刺激前观察到四种不同的血流模式：左心室（LV）血液流入右（RAo）和左（LAo）动脉，而右心室（RV）血液仅流入LAo;两个动脉接受LV和RV血液的混合物;只有LV血液灌注两个动脉; RV血液流入两个动脉，但LV血液仅流入RAo。在迷走神经刺激期间，在一半的动物中，两个心房接受LV和RV血液的混合物，在另一半中，两个心房接受RV血液，但LV血液仅流入RAo。多普勒超声心动图和对比超声心动图显示，在收缩期，在Panizza孔和左心耳底部有旋流。这些数据表明，迷走神经刺激维持或产生R-L分流，血流模式是可变的，血液可以在Panizza孔和LAo基底中旋转。
Many different flow patterns have been described through the central circulation of crocodilian reptiles. We tested the hypothesis that the vagus nerve stimulation promotes right-to-left (R-L) shunting in the alligator. Flow patterns were investigated before and during stimulation of the intact left vagus nerve using three methods. 1) Atrial and aortic PO2 were measured simultaneously and continuously by gas probes. 2) Atrial outflows were tracked with a blood tracer (helium). 3) Flows were assessed with echocardiography. Four different flow patterns were observed before vagal stimulation: left ventricular (LV) blood flowed into both the right (RAo) and left (LAo) aortas, whereas right ventricular (RV) blood flowed only into the LAo; both aortas received a mixture of LV and RV blood; only LV blood perfused both aortas; and RV blood flowed into both aortas, but LV blood flowed only into the RAo. During vagal stimulation, both aortas received a mixture of LV and RV blood in half of the animals, and in the other half, both aortas received RV blood, but LV blood flowed only into the RAo. Doppler and contrast echocardiography demonstrated swirling flow in the foramen of Panizza and the base of the LAo during systole. These data indicate that vagal stimulation either maintains or produces R-L shunting, flow patterns are variable, and blood can swirl in the foramen of Panizza and LAo base.