Core body temperature and the thermoneutral zone: a longitudinal study of normal human pregnancy
Core body temperature and the thermoneutral zone: a longitudinal study of normal human pregnancy
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DOI：
10.1111/j.1748-1716.2010.02228.x
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发表时间：
2011-04-01
影响因子：
6.3
通讯作者：
Pirhonen, J.
中科院分区：
文献类型：
--
作者：
Hartgill, T. W.;Bergersen, T. K.;Pirhonen, J.
Aim:Using a longitudinal study design, we investigated changes in maternal core temperature and ambient temperatures before and after a localized cooling procedure to the right hand.Methods:Fifteen pregnant women participated. The experiments were sequentially performed for 21 month periods on each subject: from the 8th week of gestation to 1 year after delivery on seven separate occasions (gestational weeks 8, 16, 26, 36 and 12, 24, 52 weeks post-partum). The experiments were conducted in a climactic chamber, allowing ambient temperature adjustment to each subjects' thermoneutral zone determined using Doppler ultrasound of the digital artery.Results:Maternal core temperature decreased from 37.1 degrees C (week 8) towards term, reaching a nadir (36.4 degrees C) at 12 weeks post-partum (P < 0.001). The ambient temperature required to reach the thermoneutral zone changed significantly from 26.5 degrees C (week 8) falling to its lowest point: 23.0 degrees C (week 36) (P < 0.001), then stabilized from 24 weeks post-partum.Conclusion:Maternal core temperature is highest in the first trimester but falls during pregnancy to a nadir 3 months post-partum. The ambient temperature required to reach the thermoneutral zone was 4 degrees C lower at 36 weeks of gestation compared with early pregnancy and late post-partum. Human temperature regulation is altered in pregnancy and for at least 3 months post-partum.
