Assessing individual and population variability in degenerative joint disease prevalence using generalized linear mixed models.
Assessing individual and population variability in degenerative joint disease prevalence using generalized linear mixed models.
复制标题
使用广义线性混合模型评估退行性关节疾病患病率的个体和群体变异性。
DOI:
10.1002/ajpa.24195
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发表时间:
2021
影响因子:
2.8
通讯作者:
Alonso-Llamazares C
中科院分区:
文献类型:
--
作者:
Alonso-Llamazares C
ObjectivesIn this paper, we introduce the use of generalized linear mixed models (GLMM) as a better alternative to traditional statistical methods for studying factors associated to the prevalence of degenerative joint disease (DJD) in bioarchaeological contexts.Materials and MethodsDJD prevalence was assessed for the appendicular joints and the spine of a Spanish population dated from the 15th to the 18th century. Data were analyzed using contingency tables, logistic regression models, and logistic GLMM.ResultsIn general, results from GLMMs find agreement in other methods. However, by being able to analyze the data at the level of individual bones instead of aggregated joints or limbs, GLMMs are capable of revealing associations that are not evident in other frameworks.DiscussionCurrently widely available in statistical analysis software, GLMMs can accommodate a wide array of data distributions, account for hierarchical correlations, and return estimates of DJD prevalence within individuals and skeletal locations that are unbiased by the effect of covariates. This gives clear advantages for the analysis of bioarchaeological datasets which can lead to more robust and comparable analyses across populations.
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DOI:
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发表时间:
2013
期刊:
Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen
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