Simultaneous MR/PET imaging of the human brain: Feasibility study
Simultaneous MR/PET imaging of the human brain: Feasibility study
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DOI：
10.1148/radiol.2483071927
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发表时间：
2008-09-01
期刊：
影响因子：
19.7
通讯作者：
Claussen, Claus D.
中科院分区：
文献类型：
--
作者：
Schlemmer, Heinz-Peter W.;Pichler, Bernd J.;Claussen, Claus D.
本研究的目的是应用磁共振（MR）成像兼容的正电子发射断层扫描（PET）探测器技术，对人脑和颅底进行同步MR/PET成像。PET探测器环由氧正硅酸镥（LSO）闪烁晶体与雪崩光电二极管（APD）组成，雪崩光电二极管安装在临床3-T MR成像仪中，使用鸟笼式发射/接收头部线圈。在体模研究后，两名患者同时进行了检查，使用氟18氟脱氧葡萄糖（FDG）PET和MR成像和光谱。MR/PET数据使形态学和多功能信息的准确配准成为可能。同步MR/PET成像在人类中是可行的，为新兴的分子成像领域开辟了新的可能性。(C)RSNA，2008年。
The purpose of this study was to apply a magnetic resonance (MR) imaging-compatible positron emission tomographic (PET) detector technology for simultaneous MR/PET imaging of the human brain and skull base. The PET detector ring consists of lutetium oxyorthosilicate (LSO) scintillation crystals in combination with avalanche photodiodes (APDs) mounted in a clinical 3-T MR imager with use of the birdcage transmit/receive head coil. Following phantom studies, two patients were simultaneously examined by using fluorine 18 fluorodeoxyglucose (FDG) PET and MR imaging and spectroscopy. MR/PET data enabled accurate coregistration of morphologic and multifunctional information. Simultaneous MR/PET imaging is feasible in humans, opening up new possibilities for the emerging field of molecular imaging. (C) RSNA, 2008.