Cholesterol granuloma and aspergilloma of the maxillary sinus
Cholesterol granuloma and aspergilloma of the maxillary sinus
复制标题
上颌窦胆固醇肉芽肿和曲菌瘤
DOI：
10.1007/s004050000306
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发表时间：
2001
影响因子：
2.6
通讯作者：
Nese Arzu Topal
中科院分区：
文献类型：
--
作者：
S. Sarıoğlu;U. Pabuçcuoǧlu;Nese Arzu Topal
鼻窦胆固醇肉芽肿是一种罕见的疾病。提出的发病机制是出血、引流障碍和通风障碍。据我们所知，CG与特定感染之间的联系以前从未被描述过。我们最近观察到一例58岁男性患者左上颌窦的CG和黄曲霉菌瘤，表现为鼻塞、头痛和鼻后分泌物。这两个发现之间的任何因果关系都是模糊的。曲菌球和副鼻窦CG的可疑机制似乎相似，因为有通风和引流障碍。胆固醇的积累不能归因于曲霉的细胞成分或分解产物，因为真菌质膜的主要甾醇是麦角甾醇，而不是胆固醇。
Cholesterol granuloma (CG) of the paranasal sinuses is rare. The proposed mechanisms of initiation are haemorrhage, impaired drainage and obstruction of ventilation. To the best of our knowledge, association of CG with a specific infection has not been described before. We have recently observed CG and aspergilloma ofAspergillus flavustype from the left maxillary sinus of a 58-year-old male patient presenting with nasal obstruction, headache and postnasal discharge. Any causative relationship between the two findings is obscure. The suspected mechanisms underlying aspergilloma and CG of the paranasal sinuses seems similar, since there is obstruction of ventilation and drainage. The cholesterol accumulation cannot be attributed to cellular components or breakdown products of the aspergillus as the major sterol of the plasma membranes of fungi is ergosterol, not cholesterol.