Age-Related Task Sensitivity of Frontal EEG Entropy During Encoding Predicts Retrieval
Age-Related Task Sensitivity of Frontal EEG Entropy During Encoding Predicts Retrieval
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DOI：
10.1007/s10548-013-0278-x
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发表时间：
2013-10-01
期刊：
影响因子：
2.7
通讯作者：
Upton, Neil
中科院分区：
文献类型：
--
作者：
O'Hora, Denis;Schinkel, Stefan;Upton, Neil
与年龄相关的记忆力下降可能部分是由于老化大脑中神经活动的复杂性发生了变化。电生理熵为正在进行的神经活动的复杂性提供了一个可接近的量度。在当前的研究中，我们计算了年轻人、老年人和认知衰退的老年人在编码相关(要学习)和无关(要忽略)刺激时的脑电(EEG)的排列熵。脑电熵对不同组的任务要求具有不同的敏感性，与年龄较大的拒绝参与者相比，年轻和年长的控制组对编码相关活动表现出更好的控制。编码过程中额叶脑电的任务敏感性预测了以后的提取，这与先前的证据一致，即认知能力下降与自我启动编码相关过程的能力降低有关。
Age-related declines in memory may be due in part to changes in the complexity of neural activity in the aging brain. Electrophysiological entropy provides an accessible measure of the complexity of ongoing neural activity. In the current study, we calculated the permutation entropy of the electroencephalogram (EEG) during encoding of relevant (to be learned) and irrelevant (to be ignored) stimuli by younger adults, older adults, and older cognitively declined adults. EEG entropy was differentially sensitive to task requirements across groups, with younger and older controls exhibiting greater control of encoding-related activity than older declined participants. Task sensitivity of frontal EEG during encoding predicted later retrieval, in line with previous evidence that cognitive decline is associated with reduced ability to self-initiate encoding-related processes.