High-intensity focused ultrasound for noninvasive fetal therapy
High-intensity focused ultrasound for noninvasive fetal therapy
复制标题
用于无创胎儿治疗的高强度聚焦超声
DOI：
10.1007/s10396-022-01199-2
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发表时间：
2022
影响因子：
1.8
通讯作者：
Nagatsuka Masaaki
中科院分区：
文献类型：
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作者：
Ichizuka Kiyotake;Seo Kohei;Izudepski Tetsuya;Nagatsuka Masaaki
高强度聚焦超声(HIFU)由聚焦在体内的超声束组成，通过热能和空化导致组织坏死，空化发生时不会损害任何中间组织。因此，通过从体外进行HIFU照射，可以在没有手术侵袭的情况下烧灼和治疗肿瘤。近年来，这种方法已经在临床的各个领域得到了应用，胎儿疗法也不例外，有几个临床应用的报道，主要是在基础实验中。本文综述了HIFU治疗胎儿的最新基础和临床研究结果。
High-intensity focused ultrasound (HIFU) consists of an ultrasonic beam that is focused within the body to induce tissue necrosis through both heat energy and as a result of cavitation, which occurs without damaging any intervening tissues. Therefore, it is possible to cauterize and treat tumors without surgical invasion by administering HIFU irradiation from outside the body. This approach has been clinically applied in various fields in recent years, and fetal therapy is no exception, with several clinical applications reported, mainly in basic experiments. This review summarizes the recent basic and clinical findings focusing on fetal treatment with HIFU.