THE PREVALENCE OF TYPE-I AND TYPE-II FELINE CORONAVIRUS INFECTIONS IN CATS
THE PREVALENCE OF TYPE-I AND TYPE-II FELINE CORONAVIRUS INFECTIONS IN CATS
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DOI：
10.1292/jvms.54.557
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发表时间：
1992-06-01
影响因子：
1.2
通讯作者：
KOYAMA, H
中科院分区：
文献类型：
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作者：
HOHDATSU, T;OKADA, S;KOYAMA, H
通过使用针对猫传染性腹膜炎病毒（FIPV）II型的单克隆抗体（MAb）的竞争性酶联免疫吸附试验（ELISA）和使用II型FIPV作为攻毒病毒的中和试验，确定了日本各地流行的猫冠状病毒类型。用间接荧光抗体法（IFA）检测了1,079份猫血清中FIPV Ⅱ型抗原，其中自然病例42份、慢性病病例647份、非病病例390份，阳性率分别为21.3%、138份和14.6%。在42例FIP患者中，分别有29例（69%）和13例（31%）感染FIPV I型和II型。慢性病患者中FIPV或FECV Ⅰ型感染111例（80.4%），FIPV或FECV Ⅱ型感染14例（10.1%）。所有57例明显未患病的病例似乎都感染了FIPV或FECV I型。这些结果表明，猫冠状病毒I型在日本的流行率更高
The types of feline coronaviruses that are prevalent throughout Japan were determined by competitive enzyme-linked immunosorbent assay (ELISA) using a monoclonal antibody (MAb) to feline infectious peritonitis virus (FIPV) Type II and neutralizing test using Type II FIPV as challenge virus. A total of 1,079 cat serum samples were tested by indirect fluorescent antibody (IFA) assay for FIPV Type II antigen, all 42 sample from natural cases of FIP, 138 of 647 (21.3%) from cases with some chronic diseases and 57 of 390 (14.6%) from apparently non-diseased cases were positive. Of the 42 cases with FIP, 29 (69%) and 13 (31%) were found to have infection with FIPV Types I and II, respectively. Of the cases with chronic diseases, 111 (80.4%) were shown to have infection with FIPV or FECV Type I, while 14 (10.1%) with FIPV or FECV Type II. All of the 57 apparently non-diseased cases seemed to have been infected with FIPV or FECV Type I. These results indicated that feline coronavirus Type I is more high prevalent in Japan