Maternal depressive symptoms in pediatric major depressive disorder: Relationship to acute treatment outcome
Maternal depressive symptoms in pediatric major depressive disorder: Relationship to acute treatment outcome
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DOI：
10.1097/chi.0b013e31816bfff5
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发表时间：
2008-06-01
影响因子：
13.3
通讯作者：
Emslie, Graham J.
中科院分区：
文献类型：
--
作者：
Kennard, Betsy D.;Hughes, Jennifer L.;Emslie, Graham J.
目的：在本研究中，我们在治疗开始和结束时评估母亲的抑郁症状，以探讨母亲疾病与儿童抑郁疾病和治疗之间可能的相互关系。方法：我们提供了146名儿童及其母亲的数据，他们参加了氟西汀的儿科急性治疗研究。在基线和每次治疗访问时，用儿童抑郁评定量表对患者进行评估。母亲在基线和急性治疗结束时完成抑郁症状快速调查表-自我报告。结果：在孩子的基线评估中，30%的母亲有中度到重度的抑郁症状。总体而言，母亲们报告说，在孩子的急性治疗结束时，母亲的抑郁症状有所改善，尽管母亲的抑郁并不是专门针对干预的。此外，在治疗开始和结束时，母亲的抑郁症状似乎与孩子的抑郁严重程度有关。在基线和治疗过程中，抑郁症状水平较高的母亲的孩子抑郁严重程度也较高。然而，在基线时，母亲抑郁症状与儿童抑郁严重程度的改善率没有关联。结论：本研究提示母亲抑郁程度与子女抑郁程度呈正相关。这些发现突出了儿童抑郁症急性治疗干预的潜在领域。
Objective: In the present study, we assess maternal depressive symptoms at the beginning and end of treatment to investigate the possible reciprocal relationship of maternal illness with the child's depressive illness and treatment. Method: We present data on 146 children and their mothers who were participating in a pediatric acute treatment study of fluoxetine. Patients were assessed with the Children's Depression Rating Scale-Revised at baseline and at each treatment visit. Mothers completed the Quick Inventory of Depressive Symptomatology-Self Report at baseline and end of acute treatment. Results: Thirty percent of mothers had moderate to severe levels of depressive symptoms at the child's baseline assessment. Overall, mothers reported improvement in maternal depressive symptoms at the end of their child's acute treatment, although maternal depression was not specifically targeted for intervention. Furthermore, mother's depressive symptoms appear to be associated with the child's depression severity both at the beginning and end of treatment. Mothers with higher levels of depressive symptoms had children with higher levels of depression severity at baseline and over the course of treatment. However, maternal depressive symptoms at baseline had no association with the rate of improvement of child depression severity. Conclusions: This study indicates a positive relationship between the depression severity of mothers and their children. These findings highlight potential areas of intervention in the acute treatment of childhood depression.