Power Doppler US patterns of vascularity and spectral Doppler US parameters in predicting malignancy in thyroid nodules
Power Doppler US patterns of vascularity and spectral Doppler US parameters in predicting malignancy in thyroid nodules
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DOI：
10.1016/j.crad.2006.10.003
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发表时间：
2007-03-01
影响因子：
2.6
通讯作者：
Ozgen, A. G.
中科院分区：
文献类型：
--
作者：
Tamsel, S.;Demirpolat, G.;Ozgen, A. G.
目的：本研究的目的是确定是否频谱多普勒超声（US）参数，包括阻力指数（RI）和最大收缩期流速（MSV），或血管模式可以用来区分恶性和良性甲状腺nodels.MATERIALS和METHODS：我们前瞻性地检查了169甲状腺结节134例超声引导下细针穿刺活检（FNAB）。能量多普勒超声成像确定的血管定义为无、仅结节周围或结节内。对于每个结节，RI和MSV值被记录为所获得的记录的平均值。FNAB和手术病理检查的结果，如果有，被用来作为最终诊断的证据，所有结节分类为良性或恶性。结果：7个结节被排除在研究，因为非诊断FNAB结果由于细胞或细胞学材料不足。在其余结节中，9个是恶性的（均在手术中证实），153个是良性的。在145个结节内有血管分布的结节中，9个（6.2%）为恶性，其余136个（93.8%）为良性。恶性结节结节内动脉RI平均为0.60，结节周围动脉RI平均为0.58。这些值并不显著高于良性结节相关值（分别为RI = 0.57和RI = 0.56）。恶性结节内动脉平均MSV为20.4cm/s，结节周围动脉平均MSV为35.3cm/s，与良性结节相比，差异无显著性（p > 0.05）。结论：本研究结果表明，多普勒超声特征包括血管类型、RI和MSV不是鉴别甲状腺结节良恶性的有用参数。因此，甲状腺结节的多普勒超声特征（包括血管类型、RI和MSV值）不能作为决定哪些结节应接受FNAB的诊断方法。(c)2006年皇家放射科医师学院。由爱思唯尔有限公司发布。保留所有权利。
AIM: The purpose of this study was to determine whether spectral Doppler ultrasound (US) parameters, including resistive index (RI) and maximal systolic velocity (MSV), or vascular pattern can be used to distinguish malignant from benign thyroid nodules.MATERIALS AND METHODS: We prospectively examined 169 thyroid nodules in 134 patients undergoing sonographically guided fine-needle aspiration biopsy (FNAB). Vascularity as determined by power Doppler US imaging was defined as absent, perinodular alone, or intranodular. For each nodule, the RI and MSV values were recorded as the average of the recordings obtained. Results of the FNAB and surgical pathological examination, if available, were used as a proof of final diagnosis to categorize all nodules as benign or malignant.RESULTS: Seven nodules were excluded from study because of non-diagnostic FNAB results due to hypocellular or insufficient cytological material. Of the remaining nodules, nine were malignant (all confirmed at surgery) and 153 were benign. Of the 145 nodules with intranodular vascularity, nine (6.2%) were malignant and the remaining 136 (93.8%) were benign. The malignant nodules had a mean RI of 0.60 on intranodular and 0.58 on perinodular arteries. These values were not significantly higher than those associated with benign nodules (RI = 0.57 and RI = 0.56, respectively). Malignant nodules had a mean MSV of 20.4 cm/s on intranodular and 35.3 cm/s on perinodular arteries that were also not significantly different from those associated with benign nodules (p > 0.05).CONCLUSION: The results of this study indicate that Doppler US characteristics including vascular pattern, RI and MSV are not useful parameters for distinguishing malignant from benign thyroid nodules. Therefore, Doppler US characteristics including vascular pattern, RI and MSV values of thyroid nodules can not be used as a diagnostic method to determine which nodules should undergo FNAB. (c) 2006 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.