PNEUMOCOCCAL BACTEREMIA WITH ESPECIAL REFERENCE TO BACTEREMIC PNEUMOCOCCAL PNEUMONIA

PNEUMOCOCCAL BACTEREMIA WITH ESPECIAL REFERENCE TO BACTEREMIC PNEUMOCOCCAL PNEUMONIA
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DOI:
10.7326/0003-4819-60-5-759
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发表时间:
1964-01-01
影响因子:
39.2
通讯作者:
GOLD, J
GOLD, J
中科院分区:
医学1区
文献类型:
--
作者:
AUSTRIAN, R;GOLD, J

文献摘要

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由几种肺炎球菌类型引起的感染的生物学各不相同,这种差异反映在未经治疗和经治疗的感染的侵袭性和死亡率方面的差异。有些人死于肺炎球菌感染的风险比其他人高,并且不能通过抗菌治疗或目前可用的纠正感染的生理紊乱的措施来防止死亡。现有的证据强烈表明,肺炎球菌感染的发病率和死亡率可以显着降低预防性接种的人在高风险与六个肺炎球菌荚膜多糖的制剂。为了更好地了解和控制感染,有必要重新建立以前使用的荚膜分型和其他细菌学技术。
The biology of infections caused by the several pneumococcal types varies and the dissimilarities are reflected by differences in invasiveness and mortality in both untreated and treated infections. Some persons are at higher risk of death from pneumococcal infections than others and cannot be prevented from dying either by antimicrobial therapy or by measures now available to correct the physiologic derangements of infection. Evidence extant suggests strongly that the morbidity and mortality from pneumococcal infection can be reduced significantly by prophylactic vaccination of persons at high risk with a preparation of six pneumococcal capsular polysaccharides. There is need for the reinstitution of capsular typing and of other bacteriologic techniques employed formerly for better understanding and control of the infections.