Impact of leg blood flow restriction during walking on central arterial hemodynamics.
Impact of leg blood flow restriction during walking on central arterial hemodynamics.
复制标题
步行时腿部血流限制对中央动脉血流动力学的影响。
DOI：
--
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Hirofumi Tanaka
中科院分区：
文献类型：
--
作者：
J. Sugawara;Tsubasa Tomoto;Hirofumi Tanaka
肢体血流限制（BFR）的步行运动已被证明可以增加肌肉质量和力量，即使是在低运动强度下进行。尽管越来越多的证据表明其有效性和日益普及，但BFR运动与心脏负荷相关的安全性尚未确定。本研究的目的是确定中央血流动力学的反应，在BFR运动，以评估其对心脏负荷的影响。15名表面健康的久坐或娱乐活跃的成年人（10名男性和5名女性，27 ± 1岁）以2 mph的速度进行5次2 min的恒定跑步机行走，休息1 min，双侧大腿近端有或没有BFR。测量逐搏血压和血流动力学（通过Modelflow方法），并通过一般传递函数用脉搏波分析评价中心动脉血流动力学。通过波分离分析得到入射波振幅和反射波振幅。与未使用BFR（11 ± 4% vs基线）相比，使用BFR（43 ± 5% vs基线）行走期间外周收缩压（SBP）增加幅度更大。在无BFR步行期间，主动脉SBP无显著变化，但在有BFR步行期间，主动脉SBP显著升高（43 ± 5% vs.基线）。BFR对IWA有显著影响，但对RWA无显著影响。这些发现表明，即使在慢速行走，腿部BFR诱导实质性的高血压反应的主动脉。然而，这种响应不能用增广波反射来解释。
Walking exercise with limb blood flow restriction (BFR) has been shown to increase muscular mass and strength even if it is performed at low exercise intensities. Despite mounting evidence for its efficacy and the increasing popularity, the safety of BFR exercise in relation to cardiac loads has not been established. The aim of this study was to determine the response of central hemodynamics during the BFR exercise to assess its impact on cardiac load. Fifteen apparently healthy sedentary or recreationally active adults (10 men and 5 women, 27 ± 1 yr) underwent five bouts of 2-min constant treadmill walking at 2 mph with 1-min rest intervals either with or without BFR on both proximal thighs. Beat-by-beat blood pressure and hemodynamics (via Modelflow method) were measured, and central arterial hemodynamics were evaluated with pulse wave analyses via general transfer function. Incident wave amplitude (IWA) and reflected wave amplitude (RWA) were obtained by the wave separation analysis. Peripheral systolic blood pressure (SBP) increased more substantially during walking with BFR (43 ± 5% vs. baseline) than without BFR (11 ± 4% vs. baseline). Aortic SBP did not change significantly during walking without BFR, but there was a substantial elevation in aortic SBP (43 ± 5% vs. baseline) during walking with BFR. Significant effect of BFR was seen in IWA but not in RWA. These findings suggest that even during slow-speed walking, leg BFR induces substantial hypertensive responses in the aorta. However, this response could not be explained by the augmented wave reflection.