Face stimuli effectively prevent brain-computer interface inefficiency in patients with neurodegenerative disease
Face stimuli effectively prevent brain-computer interface inefficiency in patients with neurodegenerative disease
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DOI：
10.1016/j.clinph.2012.11.006
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发表时间：
2013-05-01
影响因子：
4.7
通讯作者：
Kuebler, Andrea
中科院分区：
文献类型：
--
作者：
Kaufmann, Tobias;Schulz, Stefan M.;Kuebler, Andrea
目的：最近，我们提出了一种新的刺激模式的脑机接口（BCI）的基础上的事件相关电位（ERP），即闪烁的字符与重叠的图片的知名面孔。这种新的面孔闪烁（FF）的范例显着优于常用的字符闪烁（CF）的方法，即简单地突出显示characters.Methods：在目前的研究中，我们评估了脑机接口（BCI）的效率低下的神经退行性疾病患者的面部刺激的影响，即他们无法沟通的BCI。健康的参与者（N = 16）和那些与神经退行性疾病（N = 9）进行拼写任务使用CF和FF paradigms.Results：FF的在线性能显着增加相比，CF在这两个，健康和受损的用户。重要的是，两名在经典CF刺激下被归类为“高度低效”的患者能够使用FF高准确度地拼写。我们的研究结果特别强调了FF范式对于那些在经典刺激approach.Conclusion中记录的ERPs的信噪比较低的用户的巨大益处：总之，我们证实了先前报道的结果，现在在在线设置中系统验证，并显示FF对运动障碍用户的特别有益效果。因此，FF范例构成了针对BCI低效现象的一大步。(C)2012年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objectives: Recently, we proposed a new stimulation paradigm for brain computer interfaces (BCI) based on event-related potentials (ERP), i.e. flashing characters with superimposed pictures of well-known faces. This new face flashing (FF) paradigm significantly outperformed the commonly used character flashing (CF) approach, i.e. simply highlighting characters.Methods: In the current study we assessed the impact of face stimuli on BCI inefficiency in patients with neurodegenerative disease, i.e. on their inability to communicate by means of a BCI. Healthy participants (N = 16) and those with neurodegenerative disease (N = 9) performed spelling tasks using CF and FF paradigms.Results: Online performance with FF was significantly increased as compared to CF in both, healthy and impaired users. Importantly, two patients who were classified "highly inefficient" with the classic CF stimulation were able to spell with high accuracy using FF. Our results particularly emphasize great benefit of the FF paradigm for those users displaying low signal-to-noise ratio of the recorded ERPs in the classic stimulation approach.Conclusion: In conclusion, we confirm previously reported results now systematically validated in an online setting and display specifically beneficial effects of FF for motor-impaired users.Significance: The FF paradigm thus constitutes a big step forward against the BCI inefficiency phenomenon. (C) 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.