THE ALKALOIDS OF MARGARITARIA-INDICA .2. THE STRUCTURES OF 4-EPIPHYLLANTHINE, MARGARITARINE AND THE STRUCTURAL REVISION OF SECURINOL-A
THE ALKALOIDS OF MARGARITARIA-INDICA .2. THE STRUCTURES OF 4-EPIPHYLLANTHINE, MARGARITARINE AND THE STRUCTURAL REVISION OF SECURINOL-A
复制标题
DOI：
10.1039/p19910001863
复制
发表时间：
1991-08-01
期刊：
影响因子：
--
通讯作者：
WHITE, AH
中科院分区：
文献类型：
--
作者：
ARBAIN, D;BIRKBECK, AA;WHITE, AH
从印度珍珠树皮中提取得到新的生物碱（4-α）-4-甲氧基一叶松烷-11-酮3和3-{N-[（2-α，15-α）-14，15-二氢-11-氧代一叶松烷-15-基]-2-氨乙基}-1H-吲哚10。 它们的结构由它们的光谱性质决定。 记录并解释已知的一叶独碱生物碱（4-β）-4-甲氧基一叶独烷-11-酮2和（2-α，4-α）-4-甲氧基一叶独烷-11-酮5的高场NMR谱。 已知的生物碱一叶秋碱醇A的结构被修正为17，这是其氢溴酸盐的X-射线晶体结构测定的结果。
Extraction of the bark of Margaritaria indica has yielded the new alkaloids (4-alpha)-4-methoxysecurinan-11-one 3 and 3-{N-[(2-alpha, 15-alpha)-14, 15-dihydro-11-oxosecurinan-15-yl]-2-aminoethyl}-1H-indole 10. Their structures followed from their spectroscopic properties. High field NMR spectra for the known Securinega alkaloids (4-beta)-4-methoxysecurinan-11-one 2 and (2-alpha,4-alpha)-4-methoxysecurinan-11-one 5 were recorded and interpreted. The structure of the known alkaloid securinol A is revised to 17 as a result of an X-ray crystal structure determination of its hydrobromide.