Perspective on Terahertz Applications in Bioscience and Biotechnology
Perspective on Terahertz Applications in Bioscience and Biotechnology
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DOI：
10.1021/acsphotonics.2c00228
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发表时间：
2022-04-20
期刊：
影响因子：
7
通讯作者：
Mittleman, Daniel M.
中科院分区：
文献类型：
--
作者：
Markelz, Andrea G.;Mittleman, Daniel M.
在太赫兹科学和技术领域，目前最活跃的研究领域之一是太赫兹测量和方法与生物和医学世界的交叉。目前的活动围绕着许多不同的问题，从生物分子和大分子复合物的振动光谱研究到生物传感，再到基于无创成像技术的医学诊断。与太赫兹科学正在取得进展的许多其他领域不同，这个研究领域一直受到许多误导性观点的困扰，这些观点至少起源于20年前，并继续出现在当前的文献中。在最坏的情况下，这些不幸的观念可能会分散人们的注意力，甚至是模糊的、迷人的和有意义的结果。本文的目的是强调其中一些错误的概念，更重要的是，将它们与许多有趣的作品区分开来，这些作品是在太赫兹与生物学和医学的富有成效的结合中不断出现的。
Within the field of terahertz science and technology, one of the most active areas of current research focuses on the intersection of terahertz measurements and methods with the world of biology and medicine. Current activities revolve around numerous diverse questions, ranging from studies of the vibrational spectra of biomolecules and macromolecular complexes to biosensing to medical diagnostics based on noninvasive imaging techniques. Unlike many other areas in which terahertz science is now making inroads, this research domain has been plagued with a number of misleading ideas, which originated at least two decades ago and continue to crop up in current literature. In the worst case, these unfortunate notions can distract from, and even obscure, fascinating and meaningful results. The purpose of this Perspective is to highlight a few of these mistaken concepts and, more importantly, to distinguish them from the many interesting works that continue to emerge from the fruitful marriage of terahertz with biology and medicine.