The association between serum dehydroepiandrosterone sulfate (DHEAS) levels and job-related stress among female nurses
The association between serum dehydroepiandrosterone sulfate (DHEAS) levels and job-related stress among female nurses
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DOI：
10.35371/aoem.2019.31.e18
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发表时间：
2019-08-14
影响因子：
1.3
通讯作者：
Moon, Jai-Dong
中科院分区：
文献类型：
--
作者：
Cho, Seunghyeon;Park, Won-Ju;Moon, Jai-Dong
背景：硫酸脱氢表雄酮（DHEAS）是肾上腺分泌的一种内源性类固醇激素。DHEAS被认为对心理社会压力起保护作用。本研究的目的是探讨工作相关的压力和DHEAS的血液浓度之间的关联，根据职业紧张因素女nurs.Methods：一个横断面研究进行了118名绝经前护士从4个部门（手术室，急诊室[ER]，重症监护病房，病房）的一所大学医院。参与者都是轮班夜班工人，工作时间超过一年，平均年龄为33.5 +/- 4.8岁。结果：高工作压力组的BDI、BAI和PSQI得分均显著高于低工作压力组，高工作压力组的BDI、BAI和PSQI得分均显著高于低工作压力组。急诊科护士的工作压力源相对较多，但焦虑和抑郁水平显著低于其他组。急诊室护士DHEAS水平高于其他科室护士。差异具有显著性（p = 0.003）。此外，有一个统计学上的显着差异，即使调整后的因素，可能会影响DHEAS的水平，如年龄，体重指数，饮酒，体力活动（p = 0.039）。结论：这一结果表明，DHEAS可能发挥的作用，作为一个标志，适当的压力管理。分泌DHEAS的能力不仅仅是由于工作量或工作压力，而是取决于个人和群体如何处理和解决压力。压力的适当解决可能会影响积极的激素分泌。
Background: Dehydroepiandrosterone sulfate (DHEAS) is an endogenous steroid hormone produced by the adrenal gland. DHEAS has been suggested to play a protective role against psychosocial stress. The aim of this study was to investigate the association between job-related stress and blood concentrations of DHEAS according to occupational stress factors among female nurses.Methods: A cross-sectional study was conducted among 118 premenopausal nurses from 4 departments (operating room, emergency room [ER], intensive care unit, and ward) of a university hospital. Participants were all rotating night shift workers who have worked for over a year and mean age of 33.5 +/- 4.8 years. Data from structured questionnaires including the Korean Occupational Stress Score, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Pittsburgh Sleep Quality Index (PSQI) were used.Results: In the high job-related stressor group, scores of BDI, BAI, and PSQI were significantly higher than low-stressor group. ER nurses had relatively more work-burden related stressors, but they had significantly lower levels of anxiety and depression than other groups. And, ER nurses showed higher levels of DHEAS than the other department nurses. The differences were significant (p = 0.003). Additionally, there was a statistically significant difference even after adjusting for factors that could affect level of DHEAS, such as age, body mass index, drinking, and physical activity (p = 0.039).Conclusions: This result suggests the possibility that DHEAS may play a role as a marker of proper stress management. The capacity to secrete DHEAS is not simply due to workload or job stressor but could be determined depending on how individuals and groups deal with and resolve stress. Proper resolution of stress may affect positive hormone secretion.