Chemoradiation for definitive, preoperative, or postoperative therapy of locally advanced non-small cell lung cancer.
Chemoradiation for definitive, preoperative, or postoperative therapy of locally advanced non-small cell lung cancer.
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DOI：
10.1097/ppo.0b013e318293238d
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发表时间：
2013-05
期刊：
影响因子：
--
通讯作者：
Mehta M
中科院分区：
文献类型：
--
作者：
Feliciano J;Feigenberg S;Mehta M
在过去的几十年里，化疗和放疗的结合在局部晚期非小细胞肺癌的治疗中发挥了至关重要的作用。局部晚期非小细胞肺癌是一种异质性很强的疾病。由于这种异质性，晚期非小细胞肺癌可以根据疾病的大小、患者的并发症以及治疗医生和设施的专业知识和资源以各种不同的方式进行管理。这篇综述描述了当前治疗策略的演变，并预测了局部晚期非小细胞肺癌治疗的未来变化。
Over the last few decades, the integration of chemotherapy and radiation has played a crucial role in the management of locally advanced NSCLC. Locally advanced NSCLC is a very heterogeneous disease. Because of this heterogeneity, advanced NSCLC can be managed in various different ways depending on the bulk of disease, the comorbidities of the patient and the expertise and resources of the treating physicians and facilities. This review describes the evolution of current treatment strategies and predicted future changes for the management of locally advanced NSCLC.