The prevalence and disability burden of adult migraine in England and their relationships to age, gender and ethnicity
The prevalence and disability burden of adult migraine in England and their relationships to age, gender and ethnicity
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DOI：
10.1046/j.1468-2982.2003.00568.x
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发表时间：
2003-09-01
期刊：
影响因子：
4.9
通讯作者：
Lipton, RB
中科院分区：
文献类型：
--
作者：
Steiner, TJ;Scher, AI;Lipton, RB
本研究估计了英国成年人偏头痛的1年患病率与年龄、性别和种族等主要人口统计学变量的关系，并描述了偏头痛的一些特征，包括相应的残疾方面。对英格兰大陆16-65岁的随机样本（n = 4007）进行了电话调查，使用了先前有效的诊断访谈。回复率为76.5%。总体而言，去年有7.6%的男性和18.3%的女性报告有或没有先兆的偏头痛，符合与国际头痛协会的诊断标准非常接近的诊断标准。偏头痛的患病率随着年龄的变化而变化，在成年早期上升，在40多岁和50多岁时下降。白种人的患病率高于其他种族。大多数偏头痛患者的发作率大于或等于1/月，并且大多数患者的日常活动受到干扰的发作率大于或等于50%。平均而言，每一个在职或学生偏头痛患者每年估计损失5.7个工作日，尽管最残疾的10%占总数的85%。调查结果与其他国家的调查结果一致。如果将英格兰大陆的这些发现预测到整个英国人口，我们估计585万16-65岁的人每天经历19万次偏头痛发作，每年因此失去2500万天的工作或学习时间。在英国，偏头痛是一个重要的公共健康问题，与巨大的成本相关。
This study estimates the 1-year prevalence of migraine in adults in England in relation to the major demographic variables of age, gender and ethnicity, and describes some of its features, including aspects of consequential disability. A telephone survey was conducted of a random sample (n = 4007) of the population aged 16-65 years of mainland England using a previously validated diagnostic interview. The response rate was 76.5%. Overall, 7.6% of males and 18.3% of females reported migraine with or without aura within the last year meeting diagnostic criteria closely approximate to those of the International Headache Society. Prevalence of migraine varied with age, rising through early adult life and declining in the late 40s and early 50s. Prevalence was higher in Caucasians than in other races. Attack rates were greater than or equal to1/month in most migraineurs, and most experienced interference with daily activities in greater than or equal to50% of their attacks. On average, an estimated 5.7 working days were lost per year for every working or student migraineur, although the most disabled 10% accounted for 85% of the total. Results were in keeping with those from surveys in other countries. If these findings in mainland England are projected to the entire UK population, we estimate that 5.85 million people aged 16-65 years experience 190 000 migraine attacks every day and lose 25 million days from work or school each year because of them. Migraine is an important public health problem in the UK, associated with very substantial costs.