Cerebral aspergillosis caused by Neosartorya hiratsukae, Brazil

Cerebral aspergillosis caused by Neosartorya hiratsukae, Brazil
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DOI:
10.3201/eid0809.020073
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发表时间:
2002-09-01
影响因子:
11.8
通讯作者:
Colombo, AL
Colombo, AL
中科院分区:
医学2区
文献类型:
--
作者:
Guarro, J;Kallas, EG;Colombo, AL

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我们报告了第一例感染的新平松菌,其中分孢子状态类似烟曲霉子囊菌。这种真菌导致一名巴西妇女脑部感染,尽管接受了伊曲康唑治疗,她还是死亡了。通过直接显微镜检查、计算机断层扫描和脑磁共振成像以及病变的反复培养来确定诊断。提供了该分离物的体外抗真菌敏感性。
We report the first case of infection by Neosartorya hiratsukae, an ascomycete in which the conidial state resembles Aspergillus fumigatus. The fungus caused a brain infection in a Brazilian woman, who died despite itraconazole treatment. Diagnosis was established by direct microscopic examination, computed tomographic scan, and magnetic resonance imaging of the brain, and repeated cultures from the lesions. The in vitro antifungal susceptibility of the isolate is provided.