Long-term follow-up after cystectomy for bladder pain syndrome: pain status, sexual function and quality of life
Long-term follow-up after cystectomy for bladder pain syndrome: pain status, sexual function and quality of life
复制标题
膀胱疼痛综合征膀胱切除术后长期随访：疼痛状况、性功能和生活质量
DOI：
10.1007/s00345-018-2554-6
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发表时间：
2018
影响因子：
3.4
通讯作者：
C. Errando Smet
中科院分区：
文献类型：
--
作者：
L. Mateu Arrom;C. Gutiérrez Ruiz;O. Mayordomo Ferrer;V. Martínez Barea;J. Palou Redorta;C. Errando Smet
目的探讨膀胱疼痛综合征（BPS）患者膀胱切除术后的远期并发症、疼痛状况、性功能及生活质量。方法回顾性分析1993年以来本科因BPS行膀胱切除术的35例患者（34女1男，67±9岁）的功能变量。对保守治疗难治性BPS患者行膀胱切除术。回肠导管膀胱切除术6例（占17.1%），肛上膀胱切除术29例（占82.9%）。前瞻性研究中，患者完成疼痛问卷[BPIC-SS，疼痛视觉模拟量表（VAS）]、健康相关生活质量问卷（EQ-5D）和性功能问卷（FSFI; 2-36），对手术满意度评分（0-10），并报告他们是否会再次接受相同的手术。结果平均随访107±83个月。2例（5.7%）患者持续疼痛，1例（2.8%）患者疼痛在20个月后复发。术后观察到白天和夜间尿频和膀胱容量显著改善。21例患者完成问卷调查。BPIC-SS平均7.5±8.4分，VAS平均2.5±2.8分。14例（66.7%）患者报告在EQ-5D上没有与疼痛相关的问题，与我们的区域参考人群相似。术后发生性行为13例（61.9%），其中10例无疼痛。平均FSFI评分为9.5±9分。手术满意度为8.8±1.7，有20例（95.2%）患者会再次接受手术。结论BPS患者膀胱切除术后疼痛持续或复发的情况较少见。与疼痛相关的生活质量与一般人群相似，患者可以无痛地恢复性活动。
PurposeTo assess the long-term complications, pain status, sexual function and quality of life after cystectomy for bladder pain syndrome (BPS).MethodsWe retrospectively reviewed functional variables for 35 patients (34 women/1 man, 67 ± 9 years old) who underwent cystectomy due to BPS since 1993 in our department. Cystectomy was offered to patients with BPS refractory to conservative treatments. Six cystectomies with ileal conduit (17.1%) and 29 supratrigonal cystectomies with enterocystoplasty (82.9%) were performed. Prospectively, patients completed questionnaires on pain [BPIC-SS, visual analogue scale (VAS) for pain], health-related quality of life (EQ-5D) and sexual function (FSFI; 2–36), rated satisfaction with surgery (0–10) and reported whether they would undergo the same surgery again.ResultsMean follow-up was 107 ± 83 months. In two (5.7%) patients, pain persisted and in one patient (2.8%) pain recurred after 20 months. Significant improvements in daytime and nighttime frequency and bladder capacity were observed postoperatively. 21 patients completed questionnaires. Mean BPIC-SS was 7.5 ± 8.4, mean VAS score 2.5 ± 2.8. 14 (66.7%) patients reported no problems related to pain on the EQ-5D, similar to our regional reference population. 13 (61.9%) patients had sexual intercourse after surgery, ten of them without pain. Mean FSFI score was 9.5 ± 9. Satisfaction with surgery was 8.8 ± 1.7 and 20 (95.2%) patients would undergo the same surgery again.ConclusionPain persistence or recurrence after cystectomy for BPS is infrequent. Quality of life related to pain is similar to that in the general population and patients can resume sexual activity without pain.