High-grade invasive urothelial carcinoma with focal plasmacytoid differentiation successfully treated by transurethral resection followed by chemoradiotherapy
High-grade invasive urothelial carcinoma with focal plasmacytoid differentiation successfully treated by transurethral resection followed by chemoradiotherapy
复制标题
DOI：
10.1111/j.1442-2042.2011.02880.x
复制
发表时间：
2011-12-01
影响因子：
2.6
通讯作者：
Kubota, Yoshinobu
中科院分区：
文献类型：
--
作者：
Kawahara, Takashi;Oshiro, Hisashi;Kubota, Yoshinobu
我们报告一例高度浸润性尿路上皮癌伴膀胱浆细胞样分化。一位75岁的妇女因肉眼可见的血尿而转诊到我院。膀胱镜检查发现实性带蒂膀胱肿瘤，经尿道膀胱肿瘤切除术（turt - bt），图像显示pT1N0M0膀胱癌。组织病理学检查显示高级别侵袭性尿路上皮癌和浆细胞样癌并存。在turt - bt之后，进行了吉西他滨和奈达铂的外束放疗和化疗。膀胱肿瘤在turt - bt术后2年内未复发。
We report a case of high-grade invasive urothelial carcinoma with plasmacytoid differentiation of the urinary bladder. A 75-year-old woman was referred to our hospital because of macroscopic hematuria. Cystoscopy detected a solid pedunculated bladder tumor, and a transurethral resection of the bladder tumor (TUR-Bt) and the image findings showed pT1N0M0 bladder cancer. The histopathological examination revealed the coexistence of a large component of high-grade invasive urothelial carcinoma and a small component of plasmacytoid carcinoma. Following the TUR-Bt, external beam radiotherapy and chemotherapy with gemcitabine and nedaplatin were carried out. The bladder tumor has not recurred for 2 years after the TUR-Bt.