Going the distance: Neocentromeres make long-range contacts with heterochromatin.
Going the distance: Neocentromeres make long-range contacts with heterochromatin.
复制标题
远距离：新着丝粒与异染色质进行长距离接触。
DOI：
10.1083/jcb.201811172
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Sullivan,BethA
中科院分区：
文献类型：
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作者：
McNulty,ShannonM;Sullivan,BethA
新着丝粒是在非典型的、通常非重复的基因组位置形成的异位着丝粒。Nishimura等人（2019. J. Cell Biol. https：//doi.org/10.1083/jcb.201805003）探索了脊椎动物新着丝粒的三维结构，从而产生了通过异染色质的核聚类进行着丝粒功能和维持的模型。
Neocentromeres are ectopic centromeres that form at noncanonical, usually nonrepetitive, genomic locations. Nishimura et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201805003) explore the three-dimensional architecture of vertebrate neocentromeres, leading to a model for centromere function and maintenance via nuclear clustering with heterochromatin.