Prevalence and correlates of herpes simplex virus type 2 infection in a population-based survey of young women in low-income neighborhoods of Northern California
Prevalence and correlates of herpes simplex virus type 2 infection in a population-based survey of young women in low-income neighborhoods of Northern California
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DOI：
10.1097/00007435-200008000-00004
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发表时间：
2000-08-01
影响因子：
3.1
通讯作者：
Katz, MH
中科院分区：
文献类型：
--
作者：
Buchacz, K;McFarland, W;Katz, MH
背景：2 型单纯疱疹病毒 (HSV-2) 是最常见的性传播感染之一，可能会增强 HIV 的传播。然而，基于人群的 HSV-2 患病率和感染相关性的估计很少。目标：获得基于人群的 HSV-2 患病率估计，并确定北加州低收入社区女性感染的人口和性行为相关性。研究设计：对 18 岁女性进行随机、单阶段、整群样本横断面调查居住在 1990 年美国人口普查街区群体中家庭收入最低 10% 的 29 岁以下人群。结果：HSV-2 感染的调查加权患病率为 34.8%（95% CI，30.4-39.2），与 HSV-2 血清阳性独立相关的因素包括黑人种族、年龄较大、收入较低、奇偶性、终生男性性伴侣数量较多、性交时间较早、性工作、性行为史结论：HSV-2 的高患病率以及与性风险的密切相关性强调了 STD（包括 HIV）在年轻人口中进一步传播的可能性。社区一级 HSV-2 监测有助于有效开展健康教育、流动性病和艾滋病毒筛查以及预防和治疗服务。
Background: Herpes simplex virus type 2 (HSV-2) is one of the most common sexually transmitted infections and may enhance transmission of HIV, However, population-based estimates of HSV-2 prevalence and correlates of infection are rare.Goals: To obtain population-based estimates of HSV-2 prevalence and to identify demographic and sexual behavioral correlates of infection among women in low-income communities of Northern California.Study Design: A randomized, single-stage, cluster sample, cross-sectional survey of women age 18 to 29 years who reside in 1990 US Census block groups at the lowest tenth percentile for household income.Results: The survey-weighted prevalence of HSV-2 infection was 34.8% (95% CI, 30.4-39.2), Factors independently associated with HSV-2 seropositivity were black race, older age, lower income, parity, greater number of lifetime male sexual partners, earlier onset of sexual intercourse, sex work, history of sexually transmitted disease (STD), and cocaine use.Conclusion: The high prevalence of HSV-2 and the strong correlation with sexual risk underscores the potential for further spread of STD, including HIV, in this young population. Community-level monitoring of HSV-2 can assist in the effective targeting of outreach for health education, mobile STD and HIV screening, and prevention and treatment services.