Differential Patterns of Implicit Emotional Processing in Alzheimer's Disease and Healthy Aging
Differential Patterns of Implicit Emotional Processing in Alzheimer's Disease and Healthy Aging
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DOI：
10.3233/jad-2009-1161
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发表时间：
2009-01-01
影响因子：
4
通讯作者：
Ellgring, Heiner
中科院分区：
文献类型：
--
作者：
Garcia-Rodriguez, Beatriz;Fusari, Anna;Ellgring, Heiner
研究了年轻成人、健康老年人和轻度阿尔茨海默病（AD）患者对情绪面部表情（EFEs）的内隐记忆。内隐记忆是通过研究先前编码的刺激和新刺激对表现的影响来揭示的，这种现象被称为知觉启动。目的是评估启动模式的变化作为衰老和痴呆的功能。参与者识别来自面部动作编码系统的efe，所使用的刺激代表了快乐、悲伤、惊讶、恐惧、愤怒和厌恶的情绪。在研究阶段，参与者使用李克特量表对36张面孔的愉快程度进行评分。随后，在提示命名任务中随机呈现36个先前研究过的和36个新的efe时，测试了他们对这些efe的反应。结果表明，在老年痴呆和衰老过程中，EFEs的内隐记忆得以保留，且未观察到特定年龄对EFEs内隐记忆的影响。然而，不同的启动模式在AD患者中很明显，这可能反映了病理性脑损伤和刺激复杂性的影响。这些发现为颞叶和额叶区域的进行性神经病理变化如何影响疾病晚期的情绪处理提供了证据。
Implicit memory for emotional facial expressions (EFEs) was investigated in young adults, healthy old adults, and mild Alzheimer's disease (AD) patients. Implicit memory is revealed by the effect of experience on performance by studying previously encoded versus novel stimuli, a phenomenon referred to as perceptual priming. The aim was to assess the changes in the patterns of priming as a function of aging and dementia. Participants identified EFEs taken from the Facial Action Coding System and the stimuli used represented the emotions of happiness, sadness, surprise, fear, anger, and disgust. In the study phase, participants rated the pleasantness of 36 faces using a Likert-type scale. Subsequently, the response to the 36 previously studied and 36 novel EFEs was tested when they were randomly presented in a cued naming task. The results showed that implicit memory for EFEs is preserved in AD and aging, and no specific age-related effects on implicit memory for EFEs were observed. However, different priming patterns were evident in AD patients that may reflect pathological brain damage and the effect of stimulus complexity. These findings provide evidence of how progressive neuropathological changes in the temporal and frontal areas may affect emotional processing in more advanced stages of the disease.