Lumbar spine listhesis in older African American women.
Lumbar spine listhesis in older African American women.
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DOI：
10.1016/s1529-9430(03)00024-x
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发表时间：
2003-07-01
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影响因子：
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通讯作者：
Cauley, Jane A
中科院分区：
文献类型：
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作者：
Vogt, Molly T;Rubin, David A;Cauley, Jane A
背景情况：腰椎的退行性变化可能导致脊柱稳定性丧失和一个椎骨相对于另一个椎骨的半脱位。尸体研究和临床病例系列表明，腰椎滑脱在非洲裔美国人中可能比在白人中更常见。（前滑脱和后滑脱）以及滑脱与腰痛、身体功能和生活质量的关系。研究设计/设置：横断面研究。患者样本：共有481名年龄在65岁及以上的非洲裔美国妇女参加了骨质疏松性骨折研究。这些妇女是从巴尔的摩，马里兰州，明尼阿波利斯，明尼苏达州，匹兹堡，宾夕法尼亚州，和波特兰，或人口为基础的列表中招募的。结果测量：不适用。方法：腰椎侧位X线片数字化，并在脊柱水平L3-L4，L4-L5和L5-S1的滑脱（前滑脱和后滑脱）进行评估。获得了470名妇女的可用数据。结果：前滑脱的总患病率为58.3%，不同的脊柱节段（L3-L4为13.2%，L4-L5为36.5%，L5-S1为29.6%）。患病率随着年龄的增长而增加，但在卵巢切除妇女和目前正在接受雌激素替代治疗的妇女中较低。前滑脱与椎间盘高度无关（p> 0.05），也与背部功能无关。后滑脱发生在4%的妇女，并与椎间盘高度下降和脊柱问题和行走problems.CONCLUSIONS：前滑脱的患病率在老年非洲裔美国妇女生活在社会中的两到三倍，发现在白色妇女的年龄相仿。这种情况与背部问题频率增加无关，也不会对一般身体功能产生不利影响。后滑脱相对罕见，但与背部功能下降有关。
BACKGROUND CONTEXT: Degenerative changes in the lumbar spine may result in a loss of spinal stability and subluxation of one vertebra relative to another. Cadaveric studies and clinical case series have suggested that listhesis may be much more common in African Americans than in whites.PURPOSE: To determine the prevalence of lumbar spine listhesis (anterolisthesis and retrolisthesis) among African American women aged 65 years and older and the relationship of listhesis to low back pain, physical function and quality of life.STUDY DESIGN/SETTING: Cross-sectional study.PATIENT SAMPLE: A total of 481 African American women aged 65 years and older who were enrolled in the Study of Osteoporotic Fractures. These women were recruited from population-based listings in Baltimore, MD, Minneapolis, MN, Pittsburgh, PA, and Portland, OR.OUTCOME MEASURES: Not applicable.METHODS: Lateral radiographs of the lumbar spine were digitized, and listhesis (anterolisthesis and retrolisthesis) was assessed at spinal levels L3-L4, L4-L5 and L5-S1. Usable data were obtained for 470 women. Listhesis was defined as present when the subluxation (antero or retro) was 3 mm or more.RESULTS: The overall prevalence of anterolisthesis was 58.3% and varied by spinal level (13.2% at L3-L4, 36.5% at L4-L5 and 29.6% at L5-S1). The prevalence increased with age but was lower among oophorectomized women and those currently on estrogen replacement therapy. Anterolisthesis was not associated (p>.05) with disc height nor was it related to back function. Retrolisthesis occurred in 4% of women and was associated with decreased disc height and an increased prevalence of spinal problems and walking problems.CONCLUSIONS: The prevalence of anterolisthesis among older African American women living in the community was two to three times greater than that found in white women of a similar age. This condition was not related to an increased frequency of back problems nor did it adversely affect general physical function. Retrolisthesis was relatively rare but was associated with decreased back function.