The atomic structure of the bluetongue virus core
The atomic structure of the bluetongue virus core
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DOI：
10.1038/26694
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发表时间：
1998-10-01
期刊：
影响因子：
64.8
通讯作者：
Stuart, DI
中科院分区：
文献类型：
--
作者：
Grimes, JM;Burroughs, JN;Stuart, DI
蓝舌病病毒核心颗粒的结构已通过X射线晶体学以接近3.5埃的分辨率确定。这个直径为700埃的转录活性区室代表了如此详细确定的最大分子结构。原子结构表明大约1,000个蛋白质组分如何自组装，使用通过三角测量实现的准等效接触的经典机制和不同的方法，我们称之为几何准等效。
The structure of the core particle of bluetongue virus has been determined by X-ray crystallography at a resolution approaching 3.5 Angstrom. This transcriptionally active compartment, 700 Angstrom in diameter, represents the largest molecular structure determined in such detail. The atomic structure Indicates how approximately 1,000 protein components self-assemble, using both the classical mechanism of quasi-equivalent contacts, which are achieved through triangulation, and a different method, which we term geometrical quasi-equivalence.