Conserved and Heteroplasmy on Mitochondrial DNA Control Region in Animal
Conserved and Heteroplasmy on Mitochondrial DNA Control Region in Animal
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发表时间：
2005
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通讯作者：
Su Ying
中科院分区：
文献类型：
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作者：
Su Ying
In this paper,the mitochondrial DNA control region(D-loop) was reviewed.In terms of nucleotide substitutions,short insertions/deletions(indels),and dynamics of variable-number tandem repeats(VNTRs),D-loop are usually considered to be the most variable parts of mtDNAs.However,site mutability and structural rearrangements are not distributed randomly across the entire region,but affect particular hypervariable sites and domains.The research of mitochondrial DNA genome of D-loop focus on conserved domain and heteroplasmy contributed to nucleotide variance and number variation that altered in mitochondrial DNA hypervariable region.Most of the analysis of D-loop sequences can aid in researching the origin of animal,the animal genetic relationship identification,analysis of population variance,evolution,individual or cell recognization,and species way.
