Neurocognitive deficits associated with the hepatitis C virus among incarcerated men.
Neurocognitive deficits associated with the hepatitis C virus among incarcerated men.
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被监禁男性中与丙型肝炎病毒相关的神经认知缺陷。
DOI：
10.1080/13854046.2012.758315
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Denney,RobertL
中科院分区：
文献类型：
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作者：
Umaki,TracieM;Denney,RobertL
这项初步研究的目的是检查感染丙型肝炎病毒 (HCV) 的囚犯的认知功能，并调查神经心理状态评估可重复电池表 A (RBANS；Randolph, ) 表现之间的关系。对 43 名 HCV+ 囚犯的数据进行了回顾性审查，并与 HCV- 囚犯样本进行了比较。五个指数中的两个（注意力：U= 537.5，p= .003；r= –.32；总计：U= 643.0，p= .048；r= –.22）和四个子测试中发现显着差异：编码（U= 326.0，p<.001，r= –.53）、数字跨度（U= 634.0，p= .038,r= –.22)、故事记忆 (U= 625.5,p= .032,r= –.24) 和故事回忆 (U= 548.5,p= .004,r= –.31)，HCV 组在所有重要指标上得分较低。在这项研究中，RBANS 被证明是一种在 HCV 人群中具有临床实用性的有效措施。在这些被监禁人群中，表现模式是当前文献中的“典型”，注意力受损出现在疾病过程的早期，该研究邀请进一步探索丙型肝炎病毒高度流行的人群中所提出的认知缺陷。
The purpose of this preliminary study was to examine cognitive functioning in inmates with the hepatitis C virus (HCV) and to investigate relationships among performance on the Repeatable Battery for the Assessment of Neuropsychological Status-Form A (RBANS; Randolph, ). Data from 43 HCV+ inmates were reviewed retrospectively and compared with a sample of HCV– inmates. Significant differences were found on two of five indices (Attention:U= 537.5,p= .003;r= –.32; Total:U= 643.0,p= .048;r= –.22) and four subtests: Coding (U= 326.0,p<.001,r= –.53), Digit Span (U= 634.0,p= .038,r= –.22), Story Memory (U= 625.5,p= .032,r= –.24), and Story Recall (U= 548.5,p= .004,r= –.31), with the HCV group scoring lower on all significant measures. In this study the RBANS proved to be an efficient measure with clinical utility among an HCV population. Within this incarcerated population patterns of performance were “typical” of current literature, with impaired attention appearing earlier in the disease process, and the study invites further exploration into proposed cognitive deficits among this population where HCV is highly prevalent.