Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma.
Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma.
复制标题
食管癌和胃癌诊断中活检数量的前瞻性评估。
DOI：
10.1016/0016-5085(82)90009-9
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发表时间：
1982
期刊：
影响因子：
29.4
通讯作者：
F. Gyorkey
中科院分区：
文献类型：
--
作者：
D. Y. Graham;J. Schwartz;G. Cain;F. Gyorkey
我们进行了一项前瞻性试验，其中202例连续患者（包括47例食管癌或胃癌）获得了活检和细胞学标本。在大多数情况下，第一次活检标本得到了正确的诊断：70%的胃癌和93%的食管癌。三个额外的活检标本将产率提高到> 95%，总共七个活检标本的产率> 98%。7例活检和细胞学标本在所有患者中得到了正确的诊断。在随后被证实为恶性的所有病变中，有17%被认为是良性的。这加强了这样一种信念，即内窥镜检查发现的所有病变都应进行活检，至少应获得7份标本。
A prospective trial was performed in which biopsy and cytology specimens were obtained on 202 consecutive patients including 47 with esophageal or gastric carcinomas. The first biopsy specimen yielded a correct diagnosis in the majority of instances: 70% of gastric carcinomas and 93% of esophageal carcinomas. Three additional biopsy specimens increased the yield to >95%, a total of seven biopsy specimens yielded >98%. Seven biopsy and cytology specimens yielded the correct diagnosis in all patients. Seventeen percent of all lesions subsequently proven to be malignant were thought to be benign, endoscopically. This reinforces the belief that all lesions seen at endoscopy should have biopsies performed and at least seven specimens should be obtained.