Increased ipsilateral uterine artery vascular resistance in women with ovarian endometrioma
Increased ipsilateral uterine artery vascular resistance in women with ovarian endometrioma
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卵巢子宫内膜异位症女性同侧子宫动脉血管阻力增加
DOI：
10.1111/jog.13266
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发表时间：
2017
影响因子：
1.6
通讯作者：
Kitawaki Jo
中科院分区：
文献类型：
--
作者：
Waratani Miyoko;Mori Taisuke;Ito Fumitake;Tanaka Yukiko;Koshiba Akemi;Takahata Akiko;Kitawaki Jo
目的本研究的目的是阐明卵巢上皮性腺瘤的存在是否与血管血流受损有关。我们调查了血管流量的变化对同侧和对侧的卵巢囊肿，手术前后MethodsThis前瞻性病例对照研究包括144名妇女（卵巢囊肿[n= 40]，子宫内膜异位症卵巢囊肿[n= 33]，非卵巢囊肿[n= 17]，和正常骨盆[n= 54]）。子宫动脉（UtA）血管阻力指数采用经阴道多普勒超声测量子宫内膜的搏动指数（PI）和阻力指数（RI），采用磁共振成像测量子宫内膜UtA的直径非卵巢囊肿组（P <0.05），正常盆腔组（P < 0.01）。瘤体同侧UtA、PI、RI术后较术前明显降低（P< 0.01）。子宫内膜异位症患者同侧UtA直径明显大于对侧（P< 0.01）。结论子宫内膜异位症患者同侧UtA血管阻力可能高于对侧，提示子宫内膜异位症患者存在亚临床动脉粥样硬化的风险。
AimThe aim of this study was to elucidate whether the presence of an ovarian endometrioma is associated with impaired vascular flow. We investigated changes in vascular flow on the ipsilateral and contralateral side of the endometrioma, before and after surgery.MethodsThis prospective case–control study included 144 women (ovarian endometrioma [n= 40], endometriosis without ovarian endometrioma [n= 33], non‐endometriotic ovarian cyst [n= 17], and normal pelvis [n= 54]). The uterine artery (UtA) vascular resistance indices (pulsatility index [PI] and resistance index [RI]) were measured using transvaginal Doppler sonography, and UtA diameters were measured using magnetic resonance imaging.ResultsThe UtA PI and RI were significantly higher on the ipsilateral side of the endometrioma than on the contralateral unaffected side in the endometrioma group (P< 0.01), as well as in the non‐endometriotic ovarian cyst group (P< 0.05), and normal pelvis group (P< 0.01). The UtA PI and RI on the ipsilateral side of the endometrioma were significantly lower after cystectomy than before cystectomy (P< 0.01). The UtA diameters were significantly larger (P< 0.01) on the ipsilateral side of the endometrioma than on the contralateral side.ConclusionThe UtA‐vascular resistance might be higher on the ipsilateral side of the endometrioma than on the contralateral unaffected side, indicating a risk of subclinical atherosclerosis in women with endometriosis.