Hypervirulent Klebsiella pneumoniae.

Hypervirulent Klebsiella pneumoniae.
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DOI:
10.1093/ofid/ofu028
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发表时间:
2014-03
影响因子:
4.2
通讯作者:
Karchmer AW
Karchmer AW
中科院分区:
医学3区
文献类型:
--
作者:
Patel PK;Russo TA;Karchmer AW

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肺炎克雷伯菌的高毒力菌株与脓肿形成(通常是肝脏脓肿)和转移性扩散有关,即使在健康患者中也是如此。我们描述了这种临床综合征的一例、分离株的基因型和表型特征,并简要回顾了这种未被充分认识的综合征的流行病学、临床表现和发病机制。
Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of this underappreciated syndrome.