Myotonic dystrophy. A multisystem disease. Report of 67 cases and a review of the literature.
Myotonic dystrophy. A multisystem disease. Report of 67 cases and a review of the literature.
复制标题
强直性肌营养不良。
DOI：
10.1159/000128826
复制
发表时间：
1965
期刊：
影响因子：
--
通讯作者：
W. Pruzanski
中科院分区：
文献类型：
--
作者：
W. Pruzanski
强直性肌营养不良（MD）是一种遗传性家族性肌肉疾病。心血管[1，2]、肺[3，4]、内分泌[5]、眼[6，7]和骨骼系统[8，9，10]的受累会产生复杂多变的临床表现。本报告的动机是对67名MD患者的研究。临床表现缺乏一致性，家族分布，吞咽障碍是肺部变化的发病机制，特别是任何身体缺陷和颅骨变化。
Myotonic Dystrophy (MD) is a heredo-familial disease of the muscles. Involvem ent of the cardio-vascular [1, 2], pulm onary [3, 4], endocrine [5], ocular [6, 7], and skeletal systems [8, 9, 10] produces a complicated and variable clinical picture. The incentive to this report is the study of 67 MD patients. Lack of uniform ity of the clinical picture, familial distribution, swallowing disturbances as pathogenesis of pulm onary changes, m any physical defects and changes in the skull bones are especially noted.