TUMOR AND TREATMENT FACTORS IMPROVING OUTCOME IN STAGE-III-B CERVIX CANCER
TUMOR AND TREATMENT FACTORS IMPROVING OUTCOME IN STAGE-III-B CERVIX CANCER
复制标题
DOI：
10.1016/0360-3016(91)90143-r
复制
发表时间：
1991-01-01
影响因子：
7
通讯作者：
HANKS, GE
中科院分区：
文献类型：
--
作者：
LANCIANO, RM;MARTZ, K;HANKS, GE
本报告回顾了271例III-B期宫颈鳞状细胞癌患者，来自护理模式研究进行的三次全国调查。在三项调查中观察到局部控制和生存率的逐渐增加，这与中央旁（A点）剂量和腔内治疗的使用的逐渐增加平行。多变量分析显示盆腔疾病的程度（单侧侧壁vs.双侧侧壁vs.下1/3阴道）和腔内治疗的使用是与局部控制和生存率相关的唯一重要肿瘤和治疗因素。采用强化放疗，局部控制率超过65%，4年生存率为50%，但并发症略有增加。
This report reviews 271 patients with Stage III-B squamous cell cancer of the uterine cervix from three national surveys conducted by the Patterns of Care Study. A progressive increase in local control and survival is seen among the three surveys which parallels a progressive increase in paracentral (point A) dose and use of intracavitary treatment. Multivariate analysis reveals extent of pelvic disease (unilateral sidewall vs. bilateral sidewall vs. lower 1/3 vagina) and use of intracavitary treatment to be the only significant tumor and treatment factors associated with local control and survival. With aggresive radiotherapy, local control rates exceeding 65% and survival of 50% at 4 years can be anticipated at the expense of a small increase in complications.