Sexual desire, sexual arousal and hormonal differences in premenopausal US and Dutch women with and without low sexual desire
Sexual desire, sexual arousal and hormonal differences in premenopausal US and Dutch women with and without low sexual desire
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DOI：
10.1016/j.yhbeh.2011.03.013
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发表时间：
2011-05-01
影响因子：
3.5
通讯作者：
Laan, Ellen
中科院分区：
文献类型：
--
作者：
Heiman, Julia R.;Rupp, Heather;Laan, Ellen
尽管女性经常报告有关缺乏性欲的问题，但女性荷尔蒙状况与欲望或性唤起的主观、生理和行为指标之间的相互作用仍只得到部分探索。本研究在两个地点招募了绝经前女性，一个在美国，另一个在荷兰，并纳入了性欲和性唤起急剧变化的各种衡量标准。将 46 名符合性欲减退症 (HSDD) 标准的女性样本与 47 名没有经历过性问题 (SF) 的女性进行比较。每组中有一半人使用口服避孕药（OC）。具体目标是调查女性激素水平与其生殖器和主观性反应之间是否存在关系。记录背景人口统计和健康变量，包括口服避孕药（OC）的使用情况，分析激素（总睾酮（T）、游离睾酮（FT）、性激素结合球蛋白（SHBG）和雌二醇）以及阴道脉冲幅度和对性幻想、视觉性刺激和男性面部照片反应的欲望和唤起的自我报告测量。 HSDD 组的自我报告性唤起和欲望低于 SF 组，但仅限于未使用口服避孕药的女性。激素与性功能之间的关系根据女性是否患有 HSDD 而有所不同。与之前的文献一致。 SF 组中 FT 与生理和主观性唤起呈正相关。 HSDD 女性表现出相反的模式，FT 与主观性反应呈负相关。研究结果表明，患有 HSDD 的女性的激素和性反应之间可能存在替代关系，她们的特征与本研究中的相似。 (C) 2011 年，爱思唯尔公司出版。
The interaction between women's hormonal condition and subjective, physiological, and behavioral indices of desire or arousal remains only partially explored, in spite of frequent reports from women about problems with a lack of sexual desire. The present study recruited premenopausal women at two sites, one in the United States and the other in the Netherlands, and incorporated various measures of acute changes in sexual desire and arousal. A sample of 46 women who met criteria for Hypoactive Sexual Desire Disorder (HSDD) was compared to 47 women who experienced no sexual problems (SF). Half of each group used oral contraceptives (OCs). The specific goal was to investigate whether there is a relationship between women's hormone levels and their genital and subjective sexual responsiveness. Background demographics and health variables, including oral contraceptive (OC) use, were recorded and hormones (total testosterone (T), free testosterone (FT). SHBG, and estradiol) were analyzed along with vaginal pulse amplitude and self-report measures of desire and arousal in response to sexual fantasy, visual sexual stimuli, and photos of men's faces. Self-reported arousal and desire were lower in the HSDD than the SF group, but only for women who were not using oral contraceptives. Relationships between hormones and sexual function differed depending on whether a woman was HSDD or not. In line with prior literature. FT was positively associated with physiological and subjective sexual arousal in the SF group. The HSDD women demonstrated the opposite pattern, in that FT was negatively associated with subjective sexual responsiveness. The findings suggest a possible alternative relationship between hormones and sexual responsiveness in women with HSDD who have characteristics similar to those in the present study. (C) 2011 Published by Elsevier Inc.