THE SIGNIFICANCE OF M AND T ANTIGENS IN THE CROSS REACTIONS BETWEEN CERTAIN TYPES OF GROUP A HEMOLYTIC STREPTOCOCCI.

THE SIGNIFICANCE OF M AND T ANTIGENS IN THE CROSS REACTIONS BETWEEN CERTAIN TYPES OF GROUP A HEMOLYTIC STREPTOCOCCI.
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DOI:
10.1084/jem.71.4.539
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发表时间:
1940-03-31
期刊:
The Journal of experimental medicine
影响因子:
--
通讯作者:
Lancefield RC
Lancefield RC
中科院分区:
其他
文献类型:
--
作者:
Lancefield RC

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在任何一种菌株中,先前识别的型特异性蛋白M的出现通常与最近识别的型特异性抗原的存在完全相关,T.菌株C203例外地具有1型T物质以及3型特征的两种型特异性抗原M和T。它没有1型M抗原。虽然没有遇到其他具有类似抗原特性的菌株,但它们很可能发生,当发生异常的血清学反应时,必须怀疑这种异常的存在。
In any one strain the occurrence of the previously recognized type-specific protein, M, is usually completely correlated with the presence of the recently recognized type-specific antigen, T. Strain C203 is exceptional in having the T substance of type 1 as well as the two type-specific antigens, M and T, characteristic of type 3. It does not have the M antigen of type 1. While other strains with similar antigenic peculiarities have not been encountered, it is probable that they occur, and the existence of such anomalies must be suspected when unusual serological reactions occur.