[Antibiotic resistance in environment of animal farms].
[Antibiotic resistance in environment of animal farms].
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DOI：
10.13345/j.cjb.180177
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发表时间：
2018-08-25
期刊：
影响因子：
--
通讯作者：
Wang, Shaolin
中科院分区：
文献类型：
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作者：
Shi, Xiaomin;Wang, Shaolin
世界卫生组织已认识到抗生素耐药性是21世纪公共卫生和食品安全的严重威胁之一。抗生素抗性基因（antibiotic resistance gene，ARG）是近年来发现的一种新的污染物。目前，许多研究表明，畜牧业是ARGs的主要储存库之一。抗生素抗性细菌和抗生素抗性基因随动物粪便沿着进入环境，加速了ARG在环境中的传播。在畜禽养殖环境中，ARG和抗生素耐药菌可通过食物链、水或空气传播给人类，对公众健康构成极大威胁。本文重点介绍了抗生素耐药菌和耐药基因在畜禽养殖环境中的流行情况、ARG的滞留和传播以及抗生素耐药性研究方法，为食品动物养殖环境中抗生素耐药性风险评估提供一定的支持。
World Health Organization has recognized antibiotic resistance is one of the serious threats to public health and food-safety in the 21st century. Recently, the antibiotic resistance gene (ARG) has been widely considered as a new pollutant. Now, many studies suggested that animal farm is one of the major reservoirs of ARGs. Antibiotic resistance bacteria and antibiotic resistance genes enter the environment along with animal excrement, accelerating the spread of ARGs in the environment. In the livestock and poultry breeding environment, ARGs and antibiotic resistant bacteria could be transmitted to humans through the food chain, water or air, posing a great threat to public health. This review highlights the prevalence of antibiotic resistant bacteria and antibiotic resistant genes in livestock-breeding environment, the retention and spread of ARGs and the method used to study the antibiotic resistance, which will provide certain support for risk assessment of antimicrobial resistance in food animal breeding environment.