HIV vaccine preparedness studies in the organization for economic co-operation and development (OECD) countries
HIV vaccine preparedness studies in the organization for economic co-operation and development (OECD) countries
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DOI：
10.1080/09540120701352258
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发表时间：
2007-10-01
影响因子：
1.7
通讯作者：
Hogg, R. S.
中科院分区：
文献类型：
--
作者：
Dhalla, S.;Woods, R.;Hogg, R. S.
艾滋病毒疫苗的开发仍然是当务之急。本文系统回顾了 30 个经济合作与发展组织高收入国家的 HIV 疫苗准备研究，以确定这些国家中注射吸毒者 (IDU)、男男性行为者 (MSM) 和异性恋风险女性 (WAHR) 中 HIV 疫苗试验开发的重要因素。在我们确定的 27 篇文章中，参与意愿 (WTP) 在 8 项涉及 IDU 的研究、11 项涉及 MSM 和 1 项涉及 WAHR 的研究中进行了评估。 IDU 中的支付意愿为 41-86%，MSM 为 23-94%，WAHR 中的支付意愿为 8-1%。研究报告了招募高风险人群的情况。八项涉及 IDU 的研究、五项涉及 MSM 的研究和三项涉及 WAHR 的研究对保留率进行了评估。 IDU 保留率在 3-98% 范围内，MSM 在 70-95% 范围内，WAHR 在 67-92% 范围内。本综述深入总结了在经济合作与发展组织国家进行的艾滋病毒疫苗准备研究。
HIV vaccine development remains an urgent priority. This article is a systematic review of HIV vaccine preparedness studies in the high-income 30 Organization for Economic Co-operation and Development countries, to identify factors important for HIV vaccine trial development in injection drug users (IDU), men who have sex with men (MSM), and women at heterosexual risk (WAHR) across these countries. Of 27 articles we identified, willingness to participate (WTP) was assessed in eight studies involving IDU, 11 involving MSM, and one involving WAHR. WTP ranged in IDU at 41-86%, MSM at 23-94%, and in WAHR, it was at 8 1 %. Studies reported recruitment of high-risk individuals. Retention was assessed in eight studies involving IDU, five involving MSM, and three involving WAHR. IDU were retained at a range of 3-98%, MSM at 70-95% and WAHR at 67 92%. This review provides an in-depth summary of HIV vaccine preparedness studies that were conducted in the Organization for Economic Co-operation and Development countries.