Population based assessment of uveitis in an urban population in southern India
Population based assessment of uveitis in an urban population in southern India
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DOI：
10.1136/bjo.84.7.706
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发表时间：
2000-07-01
影响因子：
4.1
通讯作者：
Rao, GN
中科院分区：
文献类型：
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作者：
Dandona, L;Dandona, R;Rao, GN
目的 - 评估印度南部城市人口中与既往手术或创伤无关的活动性和非活动性葡萄膜炎的患病率。 方法 - 作为安得拉邦眼病研究的一部分，2522 名受试者（符合条件的人的 85.4%）（代表印度南部海得拉巴市人口的样本）接受了访谈和详细的散瞳检查。当前没有活动性炎症的葡萄膜炎后遗症的存在被定义为非活动性葡萄膜炎。结果 - 21 名受试者中存在与既往手术或创伤无关的活动性或非活动性葡萄膜炎的明确证据，年龄-性别调整后的患病率为 0.73%（95% 置信区间 (CI) 0.44-1.14%。8 名受试者中存在活动性葡萄膜炎，年龄-性别调整后的患病率 患病率为 0.37%（95% CI 0.19-0.70），其中 0.06% 为前位，0.25% 为中位，0.06% 为后位。非活动性葡萄膜炎的患病率为 0.36% (95% CI 0.17-0.68%)，包括黄斑脉络膜视网膜炎疤痕 (0.26%)、前部血管炎 (0.07%) 和先前涉及的血管炎 整个眼睛 (0.03%)。至少一只眼睛葡萄膜炎小于 6/18 的视力障碍患病率为 0.27%，至少一只眼睛小于 6/60 的患病率为 0.16%，双眼小于 6/60 的患病率为 0.03%。结论——这些基于人口的横断面数据给出了印度城市人口中各种类型葡萄膜炎患病率的估计。活动性或既往葡萄膜炎 该人群中每 140 人中就有 1 人可能在某个阶段需要治疗。
Aim-To assess the prevalence of active and inactive uveitis unrelated to previous surgery or trauma in an urban population in southern India.Methods-As part of the Andhra Pradesh Eye Disease Study, 2522 subjects (85.4% of those eligible), a sample representative of the population of Hyderabad city in southern India, underwent interview and detailed dilated eye examination. Presence of sequelae of uveitis without current active inflammation was defined as inactive uveitis.Results-Unequivocal evidence of active or inactive uveitis unrelated to previous surgery or trauma was present in 21 subjects, an age-sex adjusted prevalence of 0.73% (95% confidence interval (CI) 0.44-1.14%. Active uveitis was present in eight subjects, an age-sex adjusted prevalence of 0.37% (95% CI 0.19-0.70), of which 0.06% was anterior, 0.25% intermediate, and 0.06% posterior. The 0.36% (95% CI 0.17-0.68%) prevalence of inactive uveitis included macular chorioretinitis scars (0.26%), anterior (0.07%) and previous vasculitis involving the whole eye (0.03%). The prevalence of visual impairment due to uveitis of less than 6/18 in at least one eye was 0.27%, less than 6/60 in at least one eye was 0.16%, and less than 6/60 in both eyes was 0.03%.Conclusion-These population based cross sectional data give an estimate of the prevalence of various types of uveitis in this urban population in India. Active or past uveitis that might need treatment at some stage was present in one of every 140 people in this population.