Sleep in post-traumatic stress disorder and panic: Convergence and divergence
Sleep in post-traumatic stress disorder and panic: Convergence and divergence
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DOI：
10.1002/da.10066
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发表时间：
2003-01-01
影响因子：
7.4
通讯作者：
Leskin, GA
中科院分区：
文献类型：
--
作者：
Sheikh, JI;Woodward, SH;Leskin, GA
睡眠障碍是焦虑症的常见临床问题，特别是在创伤后应激障碍（PTSD）和惊恐障碍（PD）患者中。一些研究试图使用实验室多导睡眠图来验证这些疾病的主观睡眠主诉。这些尝试，通常集中在PTSD或PD独立，已经证明了不一致的结果。据我们所知，没有这样的研究试图直接比较和对比PTSD和PD的睡眠障碍。我们对主观睡眠障碍、睡眠结构和睡眠相关生物学现象的研究综述表明，对这两种疾病的睡眠障碍进行比较表征是及时的。这样的推断是基于我们在已发表的文献中发现的PTSD和PD之间的几个趋同和分歧领域的识别，以及我们自己的初步调查。具体来说，PTSD和PD似乎收敛于几个睡眠相关的参数，即睡眠质量，存在的情节性异睡状态，和运动时间。他们似乎也在其他重要的睡眠相关领域，如呼吸障碍和特殊的现象学性质的情节性异眠症，即噩梦或夜间恐慌发作分歧。集中在这种重叠现象的调查可能提供基础，进一步阐明这两种疾病的基础中央恐惧系统。此外，这些睡眠研究有可能为正在进行的努力提供重要的见解，以制定一个有凝聚力的概念框架，这些疾病的病理生理学。(C)2003年，WiLey-Liss，Inc.
Disturbed sleep is a common clinical problem in anxiety disorders, particularly in patients with post-traumatic stress disorder (PTSD) and panic disorder (PD). Several studies have attempted to validate the subjective sleep complaints of these disorders using laboratory polysomnography. These attempts, typically focusing on PTSD or PD independently, have demonstrated inconsistent results. To our knowledge, no such studies have attempted to directly compare and contrast sleep disturbances in PTSD and PD together. Our review of the studies of subjective sleep disturbances, sleep architecture, and sleep-related biologic phenomena suggests that a comparative characterization of sleep disturbances in these two disorders is timely. Such an inference is based on our identification of several areas of convergence and divergence between PTSD and PD found in the published literature, as well as our own preliminary investigations. Specifically, PTSD and PD seem to converge on several sleep-related parameters, namely, sleep quality, presence of episodic parasomnias, and movement time. They also appear to diverge in other important sleep-related areas such as respiratory disturbances and the particular phenomenological nature of episodic parasomnias, namely nightmares or nocturnal panic attacks. Investigations focusing on such overlapping phenomena may provide groundwork for further elucidation of central fear systems underlying these two disorders. Additionally, such sleep studies have the potential to provide important insights into ongoing efforts to develop a cohesive conceptual framework into the pathophysiologies of these disorders. (C) 2003 WiLey-Liss, Inc.