Fornix-based versus limbal-based conjunctival flaps in trabeculectomy with mitomycin C in high-risk patients.
Fornix-based versus limbal-based conjunctival flaps in trabeculectomy with mitomycin C in high-risk patients.
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DOI：
10.2147/opth.s61342
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Tanihara H
中科院分区：
文献类型：
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作者：
Kuroda U;Inoue T;Awai-Kasaoka N;Shobayashi K;Kojima S;Tanihara H
比较角膜缘和穹窿小梁切除术在有眼部切口手术史的患者中的手术结果。其中26眼行角膜缘小梁切除术（LB组），26眼行穹窿小梁切除术（FB组）。如果眼内压值≥21、≥18和≥15 mmHg（分别为条件A、B和C）或<4 mmHg，或者如果患者需要额外的青光眼手术，则回顾性记录手术失败。Kaplan-Meier生存曲线分析用于评估手术失败。对于条件A，FB组和LB组的2年手术成功率分别为75.0%和63.9%（P=0.124）。条件B的相应值分别为55.0%和61.7%（P=0.638），条件C的相应值分别为55.0%和57.0%（P=0.454）。LB组滤过泡渗漏、张力减退、脉络膜脱离和滤过泡相关感染的发生率分别为11.5%、26.9%、50.0%和7.7%。FB组的相应值分别为30.8%、23.1%、46.2%和0.0%，两组之间无统计学差异。对于有眼部切口手术史的患者，角膜缘小梁切除术和穹窿小梁切除术的手术结局无显著差异。
To compare the surgical outcomes of limbal-based and fornix-based trabeculectomy in eyes with a history of ocular incisional surgery. Twenty-six eyes underwent limbal-based trabeculectomy (group LB), and were condition matched with 26 eyes that received fornix-based trabeculectomy (group FB). Surgical failure was recorded retrospectively if the intraocular pressure value was either ≥21, ≥18, and ≥15 mmHg (conditions A, B, and C, respectively) or <4 mmHg or if the patient required additional glaucoma surgery. Kaplan–Meier survival curve analysis was used to assess surgical failure. For condition A, the 2 year surgical success probabilities were 75.0% and 63.9% in groups FB and LB, respectively (P=0.124). The corresponding values were 55.0% and 61.7% (P=0.638) in condition B, and 55.0% and 57.0% (P=0.454) in condition C. The rates of bleb leakage, hypotony, choroidal detachment, and bleb-related infection were 11.5%, 26.9%, 50.0%, and 7.7% in group LB, respectively. The corresponding values in group FB were 30.8%, 23.1%, 46.2%, and 0.0%, which were not statistically different between the two groups. No significant differences in surgical outcomes were observed between limbal-based and fornix-based trabeculectomy for patients with a history of incisional ocular surgeries.