Maximum-likelihood estimation of a hybrid index based on molecular markers

Maximum-likelihood estimation of a hybrid index based on molecular markers
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DOI:
10.1111/j.1471-8286.2005.01011.x
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发表时间:
2005-09-01
期刊:
MOLECULAR ECOLOGY NOTES
影响因子:
--
通讯作者:
Buerkle, CA
Buerkle, CA
中科院分区:
其他
文献类型:
--
作者:
Buerkle, CA

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本文阐述了一种利用遗传标记的信息来量化杂交物种对未知祖先个体的遗传贡献的杂交指数。显性标记只会导致对后代杂种指数的可靠和准确的估计。相反,共显性标记可以完全分辨,其使用是不成问题的。对于亲本物种之间差异很大的两种标记和等位基因频率(F-ST>=0.17),基于35-45个基因座的杂交指数将具有几乎最小的可信区间。杂交指数的估计对亲本等位基因频率估计的适度误差是稳健的。
This paper elaborates on a hybrid index that utilizes information from genetic markers to quantify the genetic contribution of hybridizing species to individuals of unknown ancestry. Dominant markers will only lead to reliable and accurate estimates of hybrid index in later generation hybrids. In contrast, codominant markers can be fully resolved and their use is unproblematic. For both types of markers and allele frequencies that differ substantially between parental species (F-ST >= 0.17), a hybrid index based on 35-45 loci will have a nearly minimal confidence interval. Estimates of hybrid index are robust to modest errors in estimates of parental allele frequencies.