Detection of hepatitis B surface antigen subtype adr in an epidemic of papular acrodermatitis of childhood (Gianotti's disease).
Detection of hepatitis B surface antigen subtype adr in an epidemic of papular acrodermatitis of childhood (Gianotti's disease).
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儿童丘疹性肢端皮炎（贾诺蒂病）流行中乙型肝炎表面抗原亚型 adr 的检测。
DOI：
10.18926/amo/31260
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发表时间：
1981
影响因子：
0.5
通讯作者：
H. Kimoto
中科院分区：
文献类型：
--
作者：
Susumu Kanzaki;Soichiro Kandda;Kuniko Terada;Shin Nohno;Keiichi Kumano;Kouji Narahara;H. Hayashi;H. Kimoto
儿童丘疹性肢端皮炎（PAC）最近被报道与B表面抗原（HBsAg）亚型ayw有关。1978年9月至1979年6月，我们在日本岩国市的一次小规模流行病中观察到14例PAC患者。所有患者血清均检出HBsAg。11例HBsAg分型结果显示，8例有adr决定簇，3例因抗原滴度低而无adr决定簇。结果表明，除了特定的HBsAg亚型之外，其他因素也有助于PAC的发生。
Papular acrodermatitis of childhood (PAC) has recently been reported to be associated with hepatitis B surface antigen (HBsAg) subtype ayw. Between September, 1978, and June, 1979, we saw 14 patients with PAC in a small epidemic occurring in Iwakuni City, Japan. HBsAg was detected in sera from all patients. Subtyping of HBsAg in 11 patients showed that 8 had a determinant adr and 3 had no detectable determinant because of low antigen titers. The result suggests that factors other than the specific HBsAg subtype contribute to the development of PAC.