Effects of lifestyle, personality, symptoms of anxiety and depression, and genetic predisposition on subjective sleep disturbance and sleep pattern.
Effects of lifestyle, personality, symptoms of anxiety and depression, and genetic predisposition on subjective sleep disturbance and sleep pattern.
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DOI：
10.1375/twin.1.4.176
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发表时间：
1998-12-01
期刊：
影响因子：
--
通讯作者：
Martin, N G
中科院分区：
文献类型：
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作者：
Heath, A C;Eaves, L J;Martin, N G
对睡眠模式（“短睡眠”与“长睡眠”）和主观睡眠障碍的基因型，个性，焦虑和抑郁的症状，生活方式的影响，使用调查数据的临床研究样本的成年澳大利亚双胞胎对，年龄17-88岁。当忽略基因型、个性和症状的影响时，生活方式变量似乎占睡眠障碍方差的4%，占睡眠模式方差的9%。睡眠障碍和睡眠模式的显着的遗传效应，这只是部分解释了人格和焦虑和抑郁症状的影响。睡眠障碍和生活方式之间的关联似乎可以通过个性和焦虑和抑郁症状对睡眠和生活方式的单独影响来解释（“基因型-风险因素相关性”）。几乎没有证据表明基因决定了对生活方式变量（“基因型x风险因素相互作用”）的敏感性差异。
The effects on sleep pattern ('short-sleep' versus 'long-sleep') and subjective sleep disturbance of genotype, personality, symptoms of anxiety and depression, and lifestyle, were examined using survey data on a clinically unselected sample of adult Australian twin pairs, aged 17-88 years. When the effects of genotype, personality and symptoms were ignored, lifestyle variables appeared to account for roughly 4% of the variance in sleep disturbance, and 9% of the variance in sleep pattern. Significant genetic effects on sleep disturbance and sleep pattern were found, which were only partly explained by the effects of personality and symptoms of anxiety and depression. Much of the association between sleep disturbance and lifestyle appeared to be explained by separate effects of personality and symptoms of anxiety and depression on sleep and lifestyle ('genotype-risk-factor correlation'). There was little evidence for genetically determined differences in sensitivity to the lifestyle variables ('genotype x risk-factor interaction').