Assessment of obstruction length and optimal viewing angle from biplane X-ray angiograms.

Assessment of obstruction length and optimal viewing angle from biplane X-ray angiograms.
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DOI:
10.1007/s10554-009-9509-3
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发表时间:
2010-01
影响因子:
2.1
通讯作者:
Reiber, Johan H. C.
Reiber, Johan H. C.
中科院分区:
医学4区
文献类型:
--
作者:
Tu, Shengxian;Koning, Gerhard;Jukema, Wouter;Reiber, Johan H. C.

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三维定量冠状动脉造影术(3D QCA)受到越来越多的需求的鼓励,以更好地评估血管尺寸和几何形状的介入目的。本文提出了一种基于双平面X射线血管造影的三维QCA系统。通过校正等中心偏移并通过改进对应的两个血管造影投影的极线约束,实现了血管中心线的准确和鲁棒的重建,并且其应用的再现性,保证了对障碍物长度和最佳视角的评估。通过体模实验研究了评估阻塞长度和最佳分叉视角的准确性和可变性。三维QCA测量的节段长度与真实节段长度相关性良好(r2 = 0.999),准确度和精密度分别为0.0 4 ± 0.2 5mm(P <0.0 1)。3D QCA略微低估了旋转角(差异:−1.5° ± 3.6°,P < 0.01),而成角没有观察到显著差异(差异:−0.2° ± 2.4°,P = 0.54)。总之,新的3D QCA方法可以高度准确和精确地评估阻塞长度和X射线血管造影的最佳视角。
Three-dimensional quantitative coronary angiography (3D QCA) has been encouraged by the increasing need to better assess vessel dimensions and geometry for interventional purposes. A novel 3D QCA system based on biplane X-ray angiograms is presented in this paper. By correcting for the isocenter offset and by improving the epipolar constraint for corresponding two angiographic projections, accurate and robust reconstruction of the vessel centerline is achieved and the reproducibility of its applications, e.g., the assessments of obstruction length and optimal viewing angle, is guaranteed. The accuracy and variability in assessing the obstruction length and optimal bifurcation viewing angle were investigated by using phantom experiments. The segment length assessed by 3D QCA correlated well with the true wire segment length (r 2 = 0.999) and the accuracy and precision were 0.04 ± 0.25 mm (P < 0.01). 3D QCA slightly underestimated the rotation angle (difference: −1.5° ± 3.6°, P < 0.01), while no significant difference was observed for the angulation angle (difference: −0.2° ± 2.4°, P = 0.54). In conclusion, the new 3D QCA approach allows highly accurate and precise assessments of obstruction length and optimal viewing angle from X-ray angiography.
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