Mindfulness Meditation Training and Self-Referential Processing in Social Anxiety Disorder: Behavioral and Neural Effects.
Mindfulness Meditation Training and Self-Referential Processing in Social Anxiety Disorder: Behavioral and Neural Effects.
复制标题
DOI：
10.1891/0889-8391.23.3.242
复制
发表时间：
2009-08
影响因子：
0.7
通讯作者：
Gross J
中科院分区：
文献类型：
--
作者：
Goldin P;Ramel W;Gross J
本研究旨在探讨正念减压疗法（MBSR）对社交焦虑障碍（SAD）患者自我参照加工脑行为机制的影响。16例患者接受功能磁共振成像，同时编码自我指涉，效价，和正字法的社会特质形容词的功能。MBSR后，14例患者完成了神经影像学检查。与基线相比，MBSR完成者表现出（a）自尊增加，焦虑减少，（B）积极的自我认可增加，消极的自我认可减少，（c）与注意力调节相关的大脑网络活动增加，（d）与概念-语言自我观相关的大脑系统活动减少。在被诊断为SAD的成年人中，MBSR相关的适应不良或扭曲的社会自我观的变化可能与概念自我加工和注意调节的调制有关。自我参照加工可以作为衡量正念训练效果的功能性生物行为目标。
This study examined the effects of mindfulness-based stress reduction (MBSR) on the brain-behavior mechanisms of self-referential processing in patients with social anxiety disorder (SAD). Sixteen patients underwent functional magnetic resonance imaging while encoding self-referential, valence, and orthographic features of social trait adjectives. Post-MBSR, 14 patients completed neuroimaging. Compared to baseline, MBSR completers showed (a) increased self-esteem and decreased anxiety, (b) increased positive and decreased negative self-endorsement, (c) increased activity in a brain network related to attention regulation, and (d) reduced activity in brain systems implicated in conceptual-linguistic self-view. MBSR-related changes in maladaptive or distorted social self-view in adults diagnosed with SAD may be related to modulation of conceptual self-processing and attention regulation. Self-referential processing may serve as a functional biobehavioral target to measure the effects of mindfulness training.