Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022.
Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022.
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2022年5月至6月，西班牙巴塞罗那，在12名患者的唾液、精液和其他临床样本中频繁检测到猴痘病毒DNA。
DOI：
10.2807/1560-7917.es.2022.27.28.2200503
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发表时间：
2022-07
期刊：
影响因子：
19
通讯作者：
Blanco, Jose L.
中科院分区：
文献类型：
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作者：
Peiro-Mestres, Aida;Fuertes, Irene;Camprubi-Ferrer, Daniel;Angeles Marcos, Maria;Vilella, Anna;Navarro, Mireia;Rodriguez-Elena, Laura;Riera, Josep;Catala, Alba;Martinez, Miguel J.;Blanco, Jose L.
自2022年5月以来，猴痘（MPX）疫情已在全球范围内扩大。我们通过实时PCR检测了12名患者在不同时间点收集的147份临床样本。在所有病例的唾液中都检测到MPX DNA，有时病毒载量很高。其他样本常为阳性：直肠拭子（11/12例）、鼻咽拭子（10/12例）、精液（7/9例）、尿液（9/12例）和粪便（8/12例）。这些结果提高了对病毒脱落和体液在疾病传播中可能作用的认识。
A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (11/12 cases), nasopharyngeal swab (10/12 cases), semen (7/9 cases), urine (9/12 cases) and faeces (8/12 cases). These results improve knowledge on virus shedding and the possible role of bodily fluids in disease transmission.