Dietary fat, calories, and fiber in colon cancer.

Dietary fat, calories, and fiber in colon cancer.
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DOI:
10.1006/pmed.1993.1068
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发表时间:
1993-09
影响因子:
5.1
通讯作者:
B. S. Reddy
B. S. Reddy
中科院分区:
医学2区
文献类型:
--
作者:
B. S. Reddy

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本报告的目的是:(a)概述迄今为止在人类流行病学研究和实验室动物模型中获得的关于膳食脂肪、热量和纤维与结肠癌发生之间关系的数据;(B)讨论膳食脂肪对结肠癌发生的影响是由于脂肪的特定作用还是由于相关的热量效应。虽然本报告的主要讨论将是关于实验室动物模型研究,但在适当情况下将参考人体研究。未来的研究将提供更多的证据,证明饮食中脂肪和纤维的类型以及总热量在结肠癌中的病因作用。
The purpose of this presentation is (a) to provide an overview of the data thus far obtained in human epidemiological studies and laboratory animal models on the relationship between dietary fat, calories, and fiber and colon carcinogenesis and (b) to discuss whether the effect of dietary fat on colon carcinogenesis is due to the specific action of fat or to an associated caloric effect. Although the primary discussion of this presentation will be on laboratory animal model studies, reference will be made to human studies where appropriate. Future research will produce additional evidence for the etiologic role of types of dietary fat and fiber and total calories in cancer of the colon discussed in this presentation.