New genetic mechanism, origin and population dynamic of bovine ephemeral fever virus
New genetic mechanism, origin and population dynamic of bovine ephemeral fever virus
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牛短暂热病毒新遗传机制、起源和种群动态
DOI：
10.1016/j.vetmic.2015.10.029
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发表时间：
2016-01-15
影响因子：
3.3
通讯作者：
Ding, Nai-Zheng
中科院分区：
文献类型：
--
作者：
He, Cheng-Qiang;Liu, Ya-Xin;Ding, Nai-Zheng
牛短暂热病毒(BEFV)是弹状病毒科黄斑病毒属的一种典型病毒。今天，流行的BEFV可分为三个系统地理谱系，东亚、中东和澳大利亚。在这项研究中，我们提供了证据，证明整个东亚血统起源于中东和澳大利亚血统之间的同源重组(HR)，这可能发生在20世纪40年代。据我们所知，HR以前没有被认为是BEFV的遗传机制。根据HR事件和贝叶斯估计，BEFV的三个谱系可能起源于非洲，并可能通过中东传播到亚洲和澳大利亚。此外，该病毒的种群可能在本世纪头十年大幅增加，这表明目前BEFV暴发的风险可能很高。(C)2015爱思唯尔B.V.保留所有权利。
Bovine ephemeral fever virus (BEFV) is a typical species of the genusEphemerovirus in the family Rhabdoviridae. Today, prevailing BEFV can be divided into three phylogeographic lineages, East Asia, Mideast, and Australia. In this study, we provide evidence that the whole East Asia lineage originates from a homologous recombination (HR) between the Mideast and Australia lineages that probably occurred in the 1940s. To our knowledge, HR has not been proposed before as the genetic mechanism of BEFV. According to the HR event and Bayesian estimation, the three BEFV lineages might originate from Africa, and may have spread to Asia and Australia through the Mideast. In addition, the population of the virus may have augmented significantly in the 2000s, suggesting that the risk for outbreaks of BEFV may be high at present. (C) 2015 Elsevier B.V. All rights reserved.