Protein import into mitochondria: two systems acting in tandem?
Protein import into mitochondria: two systems acting in tandem?
复制标题
DOI：
10.1016/0962-8924(91)90037-a
复制
发表时间：
1991-10-01
影响因子：
19
通讯作者：
Schatz, G
中科院分区：
文献类型：
--
作者：
Glick, B;Wachter, C;Schatz, G
线粒体可以从细胞质中两个线粒体膜紧密贴合的位置输入蛋白质。然而，这些膜中的每一个都包含独特的蛋白质易位通道。最近的证据表明，这两种类型的通道不是永久耦合的，而是可能以可逆的方式解离。这种可逆的相互作用可能对于线粒体内分选蛋白至关重要。
Mitochondria can import proteins from the cytoplasm at sites where the two mitochondrial membranes are closely apposed. However, each of these membranes contains a distinct protein translocation channel. Recent evidence suggests that the two types of channel are not permanently coupled, but may dissociate in a reversible manner. This reversible interaction is probably essential for intramitochondrial sorting proteins.