A systematic review of studies measuring health-related quality of life of general injury populations.

A systematic review of studies measuring health-related quality of life of general injury populations.
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DOI:
10.1186/1471-2458-10-783
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发表时间:
2010-12-23
期刊:
影响因子:
4.5
通讯作者:
van Beeck EF
van Beeck EF
中科院分区:
医学2区
文献类型:
--
作者:
Polinder S;Haagsma JA;Belt E;Lyons RA;Erasmus V;Lund J;van Beeck EF

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重要的是要更深入地了解伤害患者的健康相关生活质量(HRQL),以记录人们的康复途径,并量化伤害对人群健康的影响。我们进行了一个系统的审查研究测量HRQL在一般伤害人群的一般健康状况的措施,总结现有的知识。伤害研究(1995-2009年)的主要纳入标准是使用通用的健康状况措施,不限于一种特定类型的伤害。根据研究设计、使用的HRQL工具、评估时间、预测变量和检测随时间变化的能力对文章进行整理。41项研究符合入选标准,使用了24种不同的通用HRQL和功能状态指标(大多数使用的是SF-36、GOS、EQ-5D)。大多数研究采用纵向设计,但随访时间和时间不同(大多为6、12和24个月)。不同的通用健康指标能够区分亚组的健康状况,并收集出院和12个月随访之间的健康状况变化。大多数研究报告说,在受伤后的第一年内,健康问题的发病率很高。12项报告HRQL效用评分的研究显示,出院后第一年恢复相当大,但不完全。本系统性综述表明,在测量一般损伤人群HRQL的研究中,HRQL工具的使用、研究人群和评估时间点存在很大差异。这种变异性阻碍了研究之间HRQL总分的比较,并阻止了旨在量化和提高伤害随时间对人群健康影响的精确度的正式荟萃分析。
It is important to obtain greater insight into health-related quality of life (HRQL) of injury patients in order to document people's pathways to recovery and to quantify the impact of injury on population health over time. We performed a systematic review of studies measuring HRQL in general injury populations with a generic health state measure to summarize existing knowledge. Injury studies (1995-2009) were identified with main inclusion criteria being the use of a generic health status measure and not being restricted to one specific type of injury. Articles were collated by study design, HRQL instrument used, timing of assessment(s), predictive variables and ability to detect change over time. Forty one studies met inclusion criteria, using 24 different generic HRQL and functional status measures (most used were SF-36, FIM, GOS, EQ-5D). The majority of the studies used a longitudinal design, but with different lengths and timings of follow-up (mostly 6, 12, and 24 months). Different generic health measures were able to discriminate between the health status of subgroups and picked up changes in health status between discharge and 12 month follow-up. Most studies reported high prevalences of health problems within the first year after injury. The twelve studies that reported HRQL utility scores showed considerable but incomplete recovery in the first year after discharge. This systematic review demonstrates large variation in use of HRQL instruments, study populations, and assessment time points used in studies measuring HRQL of general injury populations. This variability impedes comparison of HRQL summary scores between studies and prevented formal meta-analyses aiming to quantify and improve precision of the impact of injury on population health over time.
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